Registration accuracy of 153Gd transmission images of the brain

European Journal of Nuclear Medicine and Molecular Imaging
F JacobsR Dierckx

Abstract

The aim of the study was to determine the accuracy of non-rigid nine-parameter image registrations based on 153Gd transmission computed tomography (TCT) images as compared with those based on 99mTc-ethyl cysteinate dimer (ECD) images and to assess whether normalised mutual information (NMI) or count difference (CD) should be used. TCT and ECD data were acquired in 25 randomly selected patients. Emission images were registered to an ECD template with a CD cost function. The same registration parameters were applied to the transmission images to create a TCT template. All TCT images were registered to the TCT template and the same registration parameters were applied to the ECD images. The procedure was repeated with NMI as cost function. Accuracy of both ECD-based and TCT-based registrations was assessed by comparing the normalisation parameter values and regional activities in the spatially normalised ECD images, using a mixed-model analysis of variance (ANOVA). Scheffe post hoc tests were performed. No significant differences were found between ECD/CD, ECD/NMI and TCT/CD, suggesting that ECD registration can be done with either CD or NMI, and that TCT registration using CD is equally as accurate as ECD registration. The accura...Continue Reading

References

Aug 22, 2000·European Journal of Nuclear Medicine·L ThurfjellB F Hutton
Aug 16, 2001·European Journal of Nuclear Medicine·K Van LaereR Dierckx
Jan 5, 2002·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·K PeremansR Dierckx
Mar 27, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Brian F HuttonDennys Y H Lau

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Citations

Dec 3, 2008·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·M Teresa AlbeldaJuan Carlos Frías

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