Registration between ultrasound and fluoroscopy or CT in prostate brachytherapy

Medical Physics
P FallavollitaG Fichtinger

Abstract

In prostate brachytherapy, transrectal ultrasound (TRUS) is used to visualize the anatomy, while implanted seeds can be visualized by fluoroscopy. Intraoperative dosimetry optimization is possible using a combination of TRUS and fluoroscopy, but requires localization of the fluoroscopy-derived seed cloud, relative to the anatomy as seen on TRUS. The authors propose to develop a method of registration of TRUS images and the implants reconstructed from fluoroscopy. A phantom was implanted with 48 seeds then imaged with TRUS and CT. Seeds were reconstructed from CT yielding a cloud of seeds. Fiducial-based ground-truth registration was established between the TRUS and CT. TRUS images are filtered, compounded, and registered to the reconstructed implants by using an intensity-based metric. The authors evaluated a volume-to-volume and point-to-volume registration scheme. In total, seven TRUS filtering techniques and three image similarity metrics were analyzed. The method was also tested on human subject data captured from a brachytherapy procedure. For volume-to-volume registration, noise reduction filter and normalized correlation metrics yielded the best result: An average of 0.54 +/- 0.11 mm seed localization error relative to g...Continue Reading

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Citations

Oct 14, 2011·Medical Physics·Ehsan DehghanGabor Fichtinger
Jul 13, 2012·Medical Image Analysis·Ehsan DehghanGabor Fichtinger
Mar 15, 2015·IEEE Transactions on Bio-medical Engineering·Huu-Giao NguyenJocelyne Troccaz
Jul 5, 2012·IEEE Transactions on Bio-medical Engineering·Mehdi MoradiSeptimiu Tim E Salcudean
Jan 26, 2017·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·S AlnaghyM Petasecca

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