Registry report of structural and functional cardiac abnormalities diagnosed by echocardiography in an asymptomatic population.

Postgraduate Medical Journal
Constantinos G MissourisDonald R J Singer

Abstract

The epidemiology of heart disease is changing, with rheumatic heart disease becoming less common but degenerative valve disorders, heart failure and atrial fibrillation (AF) increasing. We sought to determine the prevalence of structural cardiac abnormalities in the apparently symptom-free adult population within our prospective echocardiography (echo) registry. Our echo registry comprised echo studies and associated demographic and clinical data obtained prospectively from 362 consecutive asymptomatic subjects aged 50-74 years and without known heart disease referred between 2011 and 2012 from general practices in the South East of England. 221 echo abnormalities were detected in 178 (49%) subjects (46% men; mean (±SD) age 63.9±9.2 years; 98% Caucasian). A major abnormality was detected in seven subjects: four had a large secundum atrial septal defect, one had critical aortic stenosis, one severe mitral regurgitation and one features of hypertrophic cardiomyopathy. Twelve subjects had left ventricular systolic dysfunction with an ejection fraction (EF) <50% (of whom 10 had EF <40%). Four subjects had AF. Minor echo abnormalities were evident in the remaining 171 (47%) subjects. Abnormalities were commoner in patients with card...Continue Reading

References

Dec 1, 1979·American Heart Journal·M D CheitlinR S Bode
Jul 1, 1968·Circulation·J Ross, E Braunwald
Apr 1, 1993·Journal of the American College of Cardiology·M LindroosR Tilvis
Jul 1, 1997·Postgraduate Medical Journal·C G Missouris, G A MacGregor
Mar 5, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·James D ThomasUNKNOWN Digital Echocardiography Committee of the American Society of Echocardiography
Sep 19, 2006·Lancet·Vuyisile T NkomoMaurice Enriquez-Sarano
Nov 13, 2007·Journal of the American College of Cardiology·David S BachG Michael Deeb
Jan 22, 2008·Clinics in Sports Medicine·Fabio Pigozzi, Marta Rizzo
Mar 4, 2008·MedGenMed : Medscape General Medicine·Steven R Neish
Jun 9, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Teresa S M Tsang
Oct 22, 2010·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER Trial Investigators
Dec 15, 2010·Heart·J L d'ArcyB Bridgewater
Aug 10, 2011·BMJ : British Medical Journal·Douglas G Altman, J Martin Bland

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Citations

Oct 21, 2016·Journal of the American Geriatrics Society·Concetta Di NoraFrancesco Antonini-Canterin
Jan 15, 2022·Postgraduate Medical Journal·Jason ChaiConstantinos G Missouris

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