Regression in children with autism spectrum disorders.

Indian Journal of Pediatrics
Prahbhjot Malhi, Pratibha Singhi

Abstract

To understand the characteristics of autistic regression and to compare the clinical and developmental profile of children with autism spectrum disorders (ASD) in whom parents report developmental regression with age matched ASD children in whom no regression is reported. Participants were 35 (Mean age = 3.57 y, SD = 1.09) children with ASD in whom parents reported developmental regression before age 3 y and a group of age and IQ matched 35 ASD children in whom parents did not report regression. All children were recruited from the outpatient Child Psychology Clinic of the Department of Pediatrics of a tertiary care teaching hospital in North India. Multi-disciplinary evaluations including neurological, diagnostic, cognitive, and behavioral assessments were done. Parents were asked in detail about the age at onset of regression, type of regression, milestones lost, and event, if any, related to the regression. In addition, the Childhood Autism Rating Scale (CARS) was administered to assess symptom severity. The mean age at regression was 22.43 mo (SD = 6.57) and large majority (66.7%) of the parents reported regression between 12 and 24 mo. Most (75%) of the parents of the regression-autistic group reported regression in the la...Continue Reading

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Citations

Feb 3, 2016·Frontiers in Cellular Neuroscience·Janet K KernMark R Geier
Oct 8, 2016·Frontiers in Neuroscience·Ditza A Zachor, Esther Ben-Itzchak
Jan 12, 2017·Journal of Autism and Developmental Disorders·Kenneth D GadowRebecca J Weber
Aug 24, 2013·International Journal of Environmental Research and Public Health·Janet K KernMark R Geier
Aug 30, 2019·Journal of Autism and Developmental Disorders·Sofie BoterbergHerbert Roeyers

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