PMID: 11926569Apr 3, 2002Paper

Regression of duodenal gastric metaplasia in Helicobacter pylori positive patients with duodenal ulcer disease

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
G CiancioC Surrenti

Abstract

It is unclear whether the extent of duodenal gastric metaplasia is due to Helicobacter pylori and/or acid. To investigate the role of Helicobacter pylori eradication in the regression of duodenal gastric metaplasia in patients with duodenal ulcer maintained in acid suppression conditions. . Duodenal (anterior, superior inferior walls of first part of duodenum) and gastric antrum biopsies were obtained from 44 Helicobacter pylori positive duodenal ulcer patients. Helicobacter pylori infection was diagnosed by rapid urease test, histology and 13C-Urea Breath Test. Patients were treated with 20 mg omeprazole tid associated with 250 mg clarithromycin and 500 mg amoxycillin four times daily for 10 days and maintained with 20 mg omeprazole daily for 18 weeks. Control endoscopies were performed at 6 and 18 weeks after beginning treatment. Duodenal gastric metaplasia regression was observed in all (32/32) patients in whom Helicobacter pylori was eradicated, but in only 3 out of 6 patients in whom eradication was not achieved (p<0. 001). . The present results suggest that Helicobacter pylori eradication associated with prolonged acid suppression may represent a good therapeutic strategy to achieve duodenal gastric metaplasia regression ...Continue Reading

References

Nov 1, 1991·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·J E MadsenS Aase
Apr 1, 1990·The Journal of Infectious Diseases·M J Blaser
Dec 1, 1990·Journal of Clinical Pathology·J I WyattM F Dixon
Nov 1, 1990·The Journal of Pathology·G JohanP J Hoedemaeker
Nov 1, 1986·Journal of Clinical Pathology·S F GrayB J Rathbone
Aug 1, 1987·Journal of Clinical Pathology·J I WyattR V Heatley
Mar 1, 1995·Journal of Clinical Gastroenterology·H YangA Blum
Apr 1, 1994·Journal of Clinical Gastroenterology·O CannizzaroG Fedeli
Nov 1, 1993·Gut·L A NoachG N Tytgat
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·Y Fukuda
Jan 28, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·G TestinoM Cornaggia

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Citations

Feb 20, 2004·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·A B AdamopoulosT D Mountokalakis
Feb 16, 2000·Journal of Physiology, Paris·M Jablonská, V Stupková
Jan 28, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·G TestinoM Cornaggia
Jul 14, 2006·Journal of Clinical Pathology·C A Rubio
Sep 1, 2010·Journal of Toxicologic Pathology·Hiromitsu Watanabe
Sep 1, 2004·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·P C KonturekE G Hahn
Jul 27, 2007·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·X B LiW Z Liu
Jan 19, 2005·World Journal of Gastroenterology : WJG·Cheng-Xin WangXiao-Ling Zhao

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