Regression of hepatocellular adenoma after bariatric surgery in severe obese patients

Liver International : Official Journal of the International Association for the Study of the Liver
Tom J G GeversJan Maarten Vrolijk

Abstract

Obesity and metabolic syndrome are increasingly recognized as risk factors for hepatocellular adenomas (HCA). There is still sparse evidence whether weight loss or bariatric surgery could induce HCA regression in these patients. In this brief report we describe the effect of weight loss on HCA regression in severe obese patients that had undergone bariatric surgery in our centre. We performed an Electronic Patient Database search and included all patients who underwent bariatric surgery in our bariatric referral centre and had an ICD-10 code of benign neoplasm of liver in our centre from (2006-2017). All imaging studies of eligible patients were re-evaluated by the study radiologist. Primary outcome was change in maximal diameter of HCA. Six of 11 eligible patients were excluded because their lesions were classified as probable focal nodular hyperplasia and two were lost to follow-up. Finally, three women with solitary (n = 1) or multiple HCA (n = 2) and a body mass index (BMI) ranging between 39 and 50 kg/m2 were included. In two patients, HCA completely regressed in 1-2 years following bariatric surgery, after BMI reductions of 36%-48%. The third patient showed a reduction of >50% in diameter of the largest HCA in 2.5 years a...Continue Reading

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Citations

May 21, 2020·European Journal of Gastroenterology & Hepatology·Beverly T RodriguesAmanda J Nicoll
Aug 15, 2019·Surgical Case Reports·Kentaro OjiDaisuke Kuroda
Jul 16, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Paulo HermanFabricio Ferreira Coelho
Jan 13, 2021·Insights Into Imaging·Federica VernuccioGiuseppe Brancatelli
Mar 9, 2021·Clinical Liver Disease·Sukul MittalAmit G Singal
Mar 27, 2021·Obesity Research & Clinical Practice·Anna Carolina Batista DantasMarco Aurelio Santo
Apr 17, 2021·The American Surgeon·Trevor S SilvaVictoria V O'Connor
Oct 24, 2021·Liver International : Official Journal of the International Association for the Study of the Liver·Chelsea McDermottChristine C Hsu

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Adenoma, Liver Cell

Liver Cell Adenoma or hepatic adenoma is a rare benign tumor. It is associated with birth control use or pregnancy. Discover the latest research on Liver Cell Adenoma here.

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