Regression of Sebaceous Carcinoma of the Eyelid after a Small Incisional Biopsy: Report of Two Cases

Ocular Oncology and Pathology
Seymour BrownsteinJames Oestrelcher

Abstract

To report 2 cases of regression of sebaceous carcinoma of the eyelid after a small incisional biopsy. Clinical, imaging, and histopathological findings are presented, with a literature review on regressing ocular tumors. Our first patient was a 79-year-old man who presented with a 10-month history of progressive left upper eyelid ptosis caused by an eyelid tumor with orbital involvement and confirmed on magnetic resonance imaging. Our second patient was a 70-year-old woman who presented with ptosis with a left upper eyelid mass. Both patients underwent a small incisional biopsy of their lesion. The histopathological diagnoses in both cases were consistent with sebaceous carcinoma. Both patients refused exenteration. Follow-up clinical examination and imaging disclosed total regression of the ptosis and of the neoplasm with no sign of recurrence in both patients over a 4-year period for Case 1 and a 7-year period for Case 2. Regression following incisional biopsy of basal cell, squamous cell, and Merkel cell carcinoma, including of the eyelid, is well documented. To the best of our knowledge, our 2 cases of sebaceous carcinoma are the first to be reported with total involution clinically and on imaging of the tumor following par...Continue Reading

References

Jul 1, 1977·The British Journal of Dermatology·J ViacJ Thivolet
Nov 1, 1982·The British Journal of Ophthalmology·G E SanbornJ A Shields
Jan 1, 1994·The British Journal of Dermatology·M J HuntR S Barnetson
Sep 16, 2000·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·H BesslerL Sirota
Mar 8, 2005·Survey of Ophthalmology·Jerry A ShieldsCarol L Shields
Jan 19, 2008·Journal of Cutaneous Pathology·Brett SramekTimothy Loy
Feb 2, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Daniel A OstlerDoina Ivan
May 22, 2010·Ophthalmic Plastic and Reconstructive Surgery·Frank S HwangDaniel M Albert
Oct 12, 2013·American Journal of Ophthalmology·Frederick A Jakobiec, Pia R Mendoza
Dec 3, 2013·Ophthalmology·Tatyana MilmanRalph C Eagle
Aug 12, 2014·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Kaustubh MulaySantosh G Honavar
May 14, 2016·Ocular Oncology and Pathology·W Robert BellCharles G Eberhart

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
A RübsamE Bertelmann
Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
Efstathios T DetorakisVassilios P Kozobolis
Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Isabel BleyenIsabelle Hardy
© 2021 Meta ULC. All rights reserved