Regulating exposure of the lens of the eye to ionising radiations

Journal of Radiological Protection : Official Journal of the Society for Radiological Protection
M C Thorne

Abstract

The International Commission on Radiological Protection (ICRP) has reviewed recent epidemiological evidence suggesting that, for the lens of the eye, the threshold in absorbed dose for the induction of deleterious health effects is about 0.5 Gy. On this basis, the Commission recommends that for occupational exposure in planned exposure situations, the equivalent dose limit for the lens of the eye should be 20 mSv in a year, averaged over defined periods of 5 yr, with exposure not exceeding 50 mSv in any single year. This paper summarises the data that have been taken into account by the ICRP and critically examines whether the proposed downward revision of the dose limit is justified. Overall, it is concluded that the accumulating radiobiological and epidemiological evidence makes it more appropriate to treat cataract induction as a stochastic rather than a deterministic effect. Within this framework, it is illogical to have the same dose limit for the lens of the eye as for the whole body irradiated uniformly. This could be addressed either by removing the special dose limit for the lens of the eye, assigning it an appropriate tissue weighting factor and including it in the computation of the effective dose, or through a compo...Continue Reading

References

Jun 30, 2004·International Journal of Radiation Biology·A MinamotoM Akahoshi
Jun 20, 2007·The British Journal of Ophthalmology·John M Sparrow
Nov 18, 2011·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·C J Martin

❮ Previous
Next ❯

Citations

Aug 27, 2013·AJR. American Journal of Roentgenology·Mei-Kang YuanHsin-Bang Leu
Jul 15, 2015·Occupational and Environmental Medicine·Yulong LianJiwen Liu
Feb 1, 2014·Journal of Spinal Disorders & Techniques·Guoxin FanXiaofei Guan
Mar 28, 2017·International Journal of Radiation Biology·Lawrence T DauerEleanor A Blakely
Nov 29, 2012·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Simon BoufflerJohn Harrison
Nov 26, 2013·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·E A AinsburyA Williamson
Jun 27, 2018·Australasian Physical & Engineering Sciences in Medicine·Abbas HaghparastMohammad Rezaei

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nihon rinsho. Japanese journal of clinical medicine
Kazuo Neriishi
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
George SgourosDarrell R Fisher
© 2021 Meta ULC. All rights reserved