Regulation and function of SF/HGF during migration of limb muscle precursor cells in chicken

Developmental Biology
S HeymannT Braun

Abstract

Limb muscles of vertebrates are derived from migratory dermomyotomal cells which emanate from a limited number of somites located adjacent to the developing limb buds. We have generated additional limb buds in chicken embryos by implantation of FGF-beads into the interlimb region in order to analyze whether these somites can be programmed to supply ectopic limbs with myogenic precursor cells. We show that migrating myogenic precursor cells are released from somites at the level of the newly formed limb, even when cell migration into the natural limb has been completed. The implantation of FGF beads in the lateral plate mesoderm rapidly induces SF/HGF expression. FGF beads implanted between HH stages 10 and 12 inhibit limb bud formation or shift the normal limb position. When an additional FGF bead was implanted at the original limb position at HH stage 15, SF/HGF expression was transiently induced to low levels without inducing a new limb. This demonstrates that the initial induction of SF/HGF by FGF does not require limb formation. Expression of SF/HGF during early limb bud stages was found in the entire developing bud and the adjacent lateral plate mesoderm with direct contacts to the lateral edge of the dermomyotome. Later, ...Continue Reading

Citations

Feb 15, 2011·Cellular and Molecular Life Sciences : CMLS·Shigetoshi Yokoyama, Hiroshi Asahara
May 31, 2012·Histochemistry and Cell Biology·Faisal Yusuf, Beate Brand-Saberi
Sep 16, 2006·Anatomy and Embryology·Elena Vasyutina, Carmen Birchmeier
Oct 18, 2006·Anatomy and Embryology·Darrell J R EvansKetan Patel
Nov 7, 2000·Current Opinion in Cell Biology·C Birchmeier, H Brohmann
Oct 28, 1998·Trends in Cell Biology·C Birchmeier, E Gherardi
Dec 22, 2011·Nature Reviews. Molecular Cell Biology·Yu Xin Wang, Michael A Rudnicki
Feb 18, 2003·Journal of Anatomy·Philippa H Francis-WestKelly Anakwe
Aug 15, 1997·Genes & Development·T FlossT Braun
Jun 10, 2000·Molecular and Cellular Biology·J SuzukiH Koide
Dec 6, 1997·Current Opinion in Genetics & Development·S Tajbakhsh, G Cossu
Mar 13, 2009·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Caroline W BeckBea Christen
May 8, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Ayako HirataAkira Satoh
Mar 1, 2012·Journal of Tissue Engineering and Regenerative Medicine·Michael R WeistLisa M Larkin
Mar 26, 2011·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Peleg Hasson
May 4, 2011·Evolution & Development·Yoshie Kawashima-OhyaShigeru Kuratani
Sep 1, 2005·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Beate Brand-Saberi
Jul 9, 2004·Developmental Cell·Frank Schnorrer, Barry J Dickson
Sep 12, 2003·Developmental Cell·Lúcia E AlvaresSusanne Dietrich
Jan 13, 2015·Cellular and Molecular Life Sciences : CMLS·Xin FuPing Hu
Sep 29, 2006·Developmental Biology·Alexander BonafedeBeate Brand-Saberi
May 19, 2009·Developmental Biology·Marie-Claire DelfiniChristophe Marcelle
Jul 7, 2007·Developmental Biology·Stefano BiressiGiulio Cossu
Mar 23, 2011·Developmental Biology·Sólveig ThorsteinsdóttirFernanda Bajanca
Oct 23, 2016·Cellular and Molecular Life Sciences : CMLS·Marianne Deries, Sólveig Thorsteinsdóttir
Jul 6, 2017·Anatomia, histologia, embryologia·T H Abd-ElhamidA R Sinning
Oct 23, 1997·Developmental Dynamics : an Official Publication of the American Association of Anatomists·F CecconiP Gruss
Dec 1, 2011·Therapeutic Advances in Medical Oncology·J Rafael Sierra, Ming-Sound Tsao
Jan 16, 2019·Development, Growth & Differentiation·Eri OkamotoMikiko Tanaka
Aug 7, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Benjamin Britton WinslowAnn Campbell Burke
Mar 16, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Akira SatohKoji Tamura
Jul 19, 2008·Nature Reviews. Genetics·Robert J Bryson-Richardson, Peter D Currie
Apr 8, 2017·Frontiers in Cell and Developmental Biology·Sonya NassariClaire Fournier-Thibault
Jul 17, 2018·Development Genes and Evolution·Saori Tani-MatsuhanaKunio Inoue
Mar 6, 2017·Oncology Reports·Yun Jung ChoiJae Cheol Lee
Nov 21, 1997·Biochemical and Biophysical Research Communications·K Matsumoto, T Nakamura

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