Regulation of aquaporin-2 trafficking and its binding protein complex

Biochimica Et Biophysica Acta
Yumi Noda, Sei Sasaki

Abstract

Trafficking of water channel aquaporin-2 (AQP2) to the apical membrane is critical to water reabsorption in renal collecting ducts and its regulation maintains body water homeostasis. However, exact molecular mechanisms which recruit AQP2 are unknown. Recent studies highlighted a key role for spatial and temporal regulation of actin dynamics in AQP2 trafficking. We have recently identified AQP2-binding proteins which directly regulate this trafficking: SPA-1, a GTPase-activating protein (GAP) for Rap1, and cytoskeletal protein actin. In addition, a multiprotein "force generator" complex which directly binds to AQP2 has been discovered. This review summarizes recent advances related to the mechanism for AQP2 trafficking.

References

Nov 1, 1992·The American Journal of Physiology·N FrankiR M Hays
Sep 1, 1982·Cell·A B Fulton
Feb 14, 1995·Proceedings of the National Academy of Sciences of the United States of America·S NielsenM A Knepper
Dec 20, 1994·Proceedings of the National Academy of Sciences of the United States of America·M Spaargaren, J R Bischoff
Mar 1, 1995·The American Journal of Physiology·N FrankiR M Hays
Sep 1, 1993·The American Journal of Physiology·H SimonR M Hays
Feb 1, 1996·The Journal of Physiology·D MarplesA Taylor
Nov 1, 1996·Trends in Biochemical Sciences·L A FeigS Cantor
Feb 1, 1997·Journal of the American Society of Nephrology : JASN·S M MuldersP M Deen
Dec 24, 1997·Journal of the American Society of Nephrology : JASN·R Vargas-PoussouC Antignac
May 20, 1998·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·A Oksche, W Rosenthal
May 29, 1998·The Journal of Clinical Investigation·B K Tamarappoo, A S Verkman
Nov 27, 1998·The American Journal of Medicine·D G Bichet
Jun 4, 1999·Trends in Cell Biology·M Colledge, J D Scott
Jun 22, 1999·The Journal of Biological Chemistry·N TsukamotoN Minato
Mar 1, 2000·Trends in Biochemical Sciences·M A McNivenY Yoon
Apr 19, 2000·The Journal of Clinical Endocrinology and Metabolism·K PaselT Schöneberg
Sep 27, 2000·Journal of the American Society of Nephrology : JASN·Giovanna ValentiMaria Svelto
Oct 14, 2000·Annual Review of Cell and Developmental Biology·J E Hinshaw
Nov 1, 2000·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·P S Agutter, D N Wheatley

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Citations

Sep 5, 2007·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Miwa SuzukiKiyoshi Asahina
Jan 9, 2007·Histochemistry and Cell Biology·Takahiro HasegawaKuniaki Takata
Jun 21, 2008·Histochemistry and Cell Biology·Kuniaki TakataTakahiro Hasegawa
Dec 11, 2007·Pflügers Archiv : European journal of physiology·Yumi Noda, Sei Sasaki
Aug 6, 2010·Pflügers Archiv : European journal of physiology·Sylvain PradervandDmitri Firsov
Feb 13, 2009·Journal of Proteome Research·Nicholas A ZwangMark A Knepper
Feb 9, 2010·Proceedings of the National Academy of Sciences of the United States of America·Markus M RinschenMark A Knepper
Oct 26, 2010·The Journal of Biological Chemistry·Kayoko EtoSei Sasaki
Feb 6, 2009·The Journal of Biological Chemistry·Jason D HoffertMark A Knepper
Aug 13, 2008·Current Opinion in Nephrology and Hypertension·Dennis BrownHua A J Lu
Jul 4, 2008·American Journal of Physiology. Cell Physiology·Ming-Jiun YuMark A Knepper
Jan 29, 2010·American Journal of Physiology. Renal Physiology·Monu GoelWilliam P Schilling
Oct 25, 2007·Physiological Genomics·Panapat UawithyaMark A Knepper
Feb 11, 2012·Nihon yakurigaku zasshi. Folia pharmacologica Japonica·Yumi Noda
Jan 25, 2008·Journal of the American Society of Nephrology : JASN·Bayram EdemirEberhard Schlatter
Apr 29, 2014·Bulletin of Experimental Biology and Medicine·A V Babina, V A Lavrinenko
Dec 17, 2008·Clinical and Experimental Nephrology·Kenichi IshibashiShintaro Kondo
Jan 23, 2016·Anatomical Science International·Toshiyuki MatsuzakiKuniaki Takata
Aug 5, 2009·The International Journal of Biochemistry & Cell Biology·Yu-Hua LiYumi Noda
Jun 4, 2008·Seminars in Nephrology·Richard BouleyDennis Brown
Oct 16, 2008·Biochemical and Biophysical Research Communications·Ikuko KadohiraMasato Yasui
Nov 7, 2006·Biochemical and Biophysical Research Communications·Sunil K Saxena, Simarna Kaur
Nov 23, 2012·Molecular Membrane Biology·Alex C ConnerMatthew T Conner
Nov 24, 2011·Molecular and Cellular Endocrinology·Roland Csépányi-KömiErzsébet Ligeti
Jul 3, 2015·Biology of Reproduction·Mónica BojJoan Cerdà
Feb 9, 2018·International Journal of Molecular Sciences·Timothée LalouxFrançois Chaumont
Jun 22, 2011·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Grazia TammaMaria Svelto
Jun 15, 2007·Current Opinion in Nephrology and Hypertension·Sei Sasaki, Yumi Noda
Jan 27, 2010·Nature Reviews. Nephrology·Yumi NodaSei Sasaki
Jul 9, 2013·Journal of the American Society of Nephrology : JASN·Sung-Sen YangShih-Hua Lin
Aug 24, 2006·American Journal of Physiology. Renal Physiology·C MazzochiP R Smith
Nov 1, 2006·Expert Review of Endocrinology & Metabolism·Angela SchulzTorsten Schöneberg
Dec 21, 2007·American Journal of Physiology. Renal Physiology·L GaliziaP Ford
Apr 23, 2011·American Journal of Physiology. Renal Physiology·Hyo-Young KimTae-Hwan Kwon
Oct 2, 2009·American Journal of Physiology. Cell Physiology·Naofumi YuiShinichi Uchida
Dec 17, 2009·American Journal of Physiology. Cell Physiology·Marco T NúñezFrancisco Nualart
Dec 28, 2007·American Journal of Physiology. Cell Physiology·Núria M Pastor-SolerSylvie Breton
Aug 6, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Shamma S RahmanErika I Boesen
Oct 31, 2015·PloS One·Huiwen RenJanet D Klein

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