Regulation of CD8(+) T cell functions by RARgamma.

Seminars in Immunology
Claire GordyYou-Wen He

Abstract

Retinoic acid plays a key role in the development and function of the immune system; however, the contribution of each of the three retinoic acid receptors (RARs) to the T cell immune response is not yet well understood. Of these receptors, both RARalpha and RARgamma are expressed in T lymphocytes. While possible functional redundancy thus complicates understanding of the role of each receptor in T cells, emerging data suggest that RARalpha and RARgamma function differently in thymocyte development and that RARgamma is required for both primary and secondary CD8(+) T cell immune responses.

References

Jan 1, 1978·European Journal of Immunology·G Dennert, R Lotan
Mar 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·B BlumbergE M De Robertis
Oct 1, 1992·Trends in Biochemical Sciences·M LeidP Chambon
Nov 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·P LeroyP Chambon
Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·P KastnerP Chambon
Jul 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·A KrustP Chambon
Apr 28, 1988·Nature·N BrandA Dejean
Jan 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·G AllenbyP Chambon
Jul 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·Y YangJ D Ashwell
Mar 29, 2000·Biochemical and Biophysical Research Communications·J FritscheM Kreutz
Oct 29, 2000·American Journal of Physiology. Endocrinology and Metabolism·Y DevauxD Ungureanu-Longrois
Mar 21, 2003·Journal of Clinical Immunology·Mark BallowCheryl Allen
Mar 21, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Eva SzegezdiZsuzsa Szondy
Jul 4, 2003·Nature·J Rodrigo MoraUlrich H Von Andrian
Mar 3, 2004·European Journal of Immunology·Beáta TóthZsuzsa Szondy
Oct 16, 2004·Immunity·Makoto IwataSi-Young Song
Feb 6, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ivan DzhagalovYou-Wen He

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Citations

May 23, 2014·International Immunology·Neil C SheppardFrank Wegmann
Aug 27, 2021·Cancer Medicine·Till KaemmererMarkus Reinholz
Oct 26, 2010·Biochimica Et Biophysica Acta·Vanessa Duong, Cécile Rochette-Egly

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