Regulation of enzymes of ethanol metabolism in yeast (Rhodotorula gracilis)

Experientia
G M HanozetA Guerritore

Abstract

The three enzymes of ethanol metabolism alcohol dehydrogenase, aldehyde dehydrogenase and acetyl-CoA synthetase in the obligate aerobic yeast Rhodotorula gracilis are repressed by glucose and induced by C2 metabolic fuels with a regulatory pattern indicating a correlation in the control mechanisms. To try an identification of the molecular signals involved in the transmission of the inducing stimulus, experiments were carried out by blocking with 2 mM pyrazole the ethanol acetaldehyde metabolic step. Results indicate that ethanol is not specifically required as a molecular signal for induction.

References

Oct 20, 1975·Biochimica Et Biophysica Acta·M WiesenfeldR Crokaert
Jul 1, 1967·Archives of Biochemistry and Biophysics·P K Maitra, R W Estabrook
Jul 1, 1967·Archives of Biochemistry and Biophysics·P K Maitra, R W Estabrook
Jan 1, 1969·Biochimica Et Biophysica Acta·H M HeickN Begin-Heick

Citations

Mar 1, 1989·European Journal of Biochemistry·M Pilone SimonettaS Ronchi

Related Concepts

Acetaldehyde
Acetic Acids
Acetate-CoA Ligase
Alcohol Oxidoreductases
Ethanol
Aldehyde Oxidoreductases
Coenzyme A Ligases
Enzyme Induction
Genes, Regulator
Pyrazoles

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