Regulation of fetal lung development in response to maternal overnutrition

Clinical and Experimental Pharmacology & Physiology
Mitchell LockJanna L Morrison


With the worldwide obesity epidemic, the proportion of women entering pregnancy overweight or obese has increased significantly in recent years. Babies born to obese women are at an increased risk of respiratory complications at birth and in childhood. In addition to maternal diabetes, there are a number of metabolic changes that the fetus of an overnourished mother experiences in utero that may modulate lung development and represent the mechanisms underlying the increased risk of respiratory complications. Herein we highlight a series of factors associated with the intrauterine environment of an overnourished mother that may impact on fetal lung development and lead to an increased risk of complications at birth or in postnatal life.


Jul 1, 1979·Journal of Steroid Biochemistry·B E Murphy
Feb 12, 1976·The New England Journal of Medicine·M F RobertM E Avery
Aug 1, 1992·American Journal of Respiratory Cell and Molecular Biology·S H GuttentagJ Floros
Apr 1, 1989·The Journal of Clinical Investigation·H G LileyP L Ballard
Nov 1, 1987·Journal of Applied Physiology·D WarburtonT Saluna
Aug 1, 1988·The Journal of Clinical Endocrinology and Metabolism·E A Ryan, L Enns
Sep 1, 1986·Clinical Obstetrics and Gynecology·K C Pringle
Mar 1, 1985·Pediatric Research·J R Bourbon, P M Farrell
Feb 1, 1984·Journal of Developmental Physiology·J A Kitterman
Jan 1, 1984·Annual Review of Physiology·P H Burri
Aug 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J A KittermanR K Creasy
Oct 1, 1995·Pediatric Research·S A Dekowski, J M Snyder
May 1, 1996·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·A LohningerR Marz
May 1, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·S Y NamK B Huh
Apr 8, 1998·Archives of Pediatrics & Adolescent Medicine·L CorderoS G Gabbe
Oct 13, 1998·Diabetes Research and Clinical Practice·L Aerts, F A Van Assche
Nov 14, 1998·Biochimica Et Biophysica Acta·J Goerke
Nov 14, 1998·Biochimica Et Biophysica Acta·R VeldhuizenF Possmayer
May 9, 2000·The American Journal of Clinical Nutrition·N F Butte
Jun 14, 2000·American Journal of Respiratory and Critical Care Medicine·R P MarshallG J Laurent
Oct 18, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·A M LeVineT R Korfhagen
Feb 15, 2001·International Journal of Epidemiology·Y B CheungJ P Karlberg
Feb 15, 2001·American Journal of Obstetrics and Gynecology·M L CockR Harding
May 23, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·S A Rooney
Jun 21, 2001·Pediatric Pulmonology·R J BoltH A Delemarre-van de Waal
Jul 27, 2001·Best Practice & Research. Clinical Endocrinology & Metabolism·J W Tomlinson, P M Stewart
Feb 13, 2002·American Journal of Physiology. Lung Cellular and Molecular Physiology·J S TordayL P Rubin
Sep 6, 2002·The Journal of Clinical Endocrinology and Metabolism·Jane E RamsayNaveed Sattar
Nov 20, 2002·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·S HundertmarkJ R Seckl
May 16, 2003·American Journal of Obstetrics and Gynecology·Sheree L BouletMaryAnn Pass
Jun 26, 2003·Clinical and Experimental Immunology·V Sánchez-MargaletC Gonzalez-Yanes

❮ Previous
Next ❯


Oct 15, 2013·Clinical and Experimental Pharmacology & Physiology·Janna L MorrisonJane Black
Jan 29, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Dan WangChao Chen
Aug 25, 2015·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Mitchell C LockJanna L Morrison
Jun 27, 2018·Pediatric Pulmonology·Atar Ben-ShmuelAsnat Walfisch
Oct 17, 2018·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Janna L MorrisonRoss L Tellam
Feb 14, 2019·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Hijab AhmedStyliani Goulopoulou
May 2, 2019·American Journal of Physiology. Lung Cellular and Molecular Physiology·Kathryn M HeyobLynette K Rogers
Oct 20, 2015·Endocrinology·M J De BlasioA J Forhead
Jan 8, 2021·Journal of Developmental Origins of Health and Disease·Jiaqi RenJanna L Morrison
Apr 25, 2021·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Margaret A AdgentKecia N Carroll
Jul 3, 2021·Frontiers in Medicine·Celien Kuiper-MakrisMiguel A Alejandre Alcazar

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.