PMID: 11934612Apr 6, 2002Paper

Regulation of flagellar assembly

Current Opinion in Microbiology
Phillip D Aldridge, K T Hughes

Abstract

Research on the molecular mechanism of bacterial flagellar assembly has been an ongoing study that spans three decades. Early work showed that regulation of flagellar gene transcription was coupled to the assembly process. Recent advances in the understanding of the regulation of flagellar assembly have shown that translational and post-translational regulation also plays a significant role in flagellar assembly. In both Salmonella and Caulobacter crescentus, translational regulation influences the secretion of the anti-sigma(28) factor FlgM and the flagellin fljK, respectively. Post-translational regulatory mechanisms also control the length of the hook and the ability of the type III secretion system to discriminate between middle and late secretion substrates. The flagellum provides a model system for understanding how gene regulation functions to ensure the efficient assembly of a complex structure and fundamental mechanisms common to all type III secretion systems.

References

Apr 29, 2000·Trends in Microbiology·J C Bennett, C Hughes
Jun 13, 2000·Journal of Bacteriology·Y K Kim, L L McCarter
Aug 31, 2000·Cell·J E KarlinseyK T Hughes
Dec 6, 2000·Microbiology and Molecular Biology Reviews : MMBR·G S Chilcott, K T Hughes
May 5, 2001·Trends in Microbiology·P Aldridge, K T Hughes
Aug 31, 2001·Microbiology and Molecular Biology Reviews : MMBR·L L McCarter

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Citations

Jan 1, 2010·Cellular and Molecular Life Sciences : CMLS·Janet E DeaneSusan M Lea
Nov 13, 2008·Antonie van Leeuwenhoek·David J CastilloGeorges Dreyfus
Oct 12, 2012·Biomedical Microdevices·Masaru KojimaToshio Fukuda
Jun 14, 2005·Current Opinion in Biotechnology·Thomas Scheibel
Dec 10, 2003·Current Opinion in Microbiology·Ellen M Quardokus, Yves V Brun
Apr 23, 2004·Current Opinion in Structural Biology·Chern-Sing GohMark Gerstein
Apr 5, 2005·Nature Biotechnology·Katariina MajanderBenita Westerlund-Wikström
Jun 13, 2013·Nature Communications·David Yu ZhangErik Winfree
Jun 25, 2008·Proceedings of the National Academy of Sciences of the United States of America·D Ewen CameronJohn J Mekalanos
Oct 11, 2008·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Raphael Simon, Charles E Samuel
Dec 13, 2006·Genes & Development·Aimee ShenDarren E Higgins
Jun 7, 2011·Applied and Environmental Microbiology·Sara SalvettiSonia Senesi
May 27, 2008·Applied and Environmental Microbiology·Matthias RabergAlexander Steinbüchel
Jun 3, 2006·Journal of Bacteriology·Phillip AldridgeKelly T Hughes
Jun 2, 2009·Journal of Bacteriology·Robert BelasRooge Suvanasuthi
Jul 24, 2007·Journal of Bacteriology·Renyi Liu, Howard Ochman
Sep 19, 2006·Journal of Bacteriology·Guinevere L LykkenTimothy L Yahr
Sep 18, 2007·Journal of Bacteriology·Javier de la MoraGeorges Dreyfus
Nov 13, 2007·Journal of Bacteriology·Alan J Wolfe, Karen L Visick
Mar 23, 2010·Journal of Bacteriology·Chunhao LiNyles W Charon
Sep 19, 2006·Journal of Bacteriology·Christine RotterBirgit Scharf
May 13, 2008·Journal of Bacteriology·Supreet SainiChristopher V Rao
Jul 26, 2011·Journal of Bacteriology·Markus WilhelmsSusana Merino

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