Jan 1, 1976

Regulation of fodder yeast Candida tropicalis glutamine synthetase activity by the end products of glutamine metabolism

Biokhimii︠a︡
V L KretovichT L Auerman

Abstract

Effect of different products of glutamine metabolism on the activity of glutamine synthetase in the presence of Mg2+, and Mn2+ and Co2+ as cofactors is studied. All the metabolites studied are found to inhibit the glutamine synthetase activity in the presence of any cation listed. The degree and the character of the inhibition by one or other metabolite depended in a considerable degree on the nature of the cation presented in the reaction mixture (Mg2+, Mn2+ or Co2+). The mechanism of the cumulative effect of retroinhibitors under the change of Mg2+ or Mn2+ in the reaction mixture was the same.

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Mentioned in this Paper

Manganese
Glutamate-ammonia Ligase Activity
Glutamate-Ammonia Ligase
Menopause
GLUL gene
Cations
Candida tropicalis allergenic extract
Metabolic Inhibition
Catalysis
Metabolite

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