Regulation of human oviductin mRNA expression in vivo

Fertility and Sterility
Christine Briton-JonesChristopher Haines

Abstract

To examine changes in oviductin mRNA expression in oviductal mucosal tissue from fertile women throughout an ovulatory cycle. Semiquantitative reverse-transcriptase-polymerase chain reaction (RT-PCR) analysis of oviductin mRNA. University-based obstetrics and gynecology department. Twenty women undergoing laparoscopy for tubal sterilization or hysterectomy for uterine fibroids. The mucosal layer was isolated from the oviduct tissue, and semiquantitative RT-PCR was performed. The relationship between serum estradiol, luteinizing hormone, and progesterone concentrations and the expression of oviductin mRNA. There was a significant positive correlation between serum estradiol and luteinizing hormone concentrations and oviductin mRNA expression. There was a significant inverse correlation between serum progesterone concentrations and oviductin mRNA expression. Little is known about the regulation of human oviductin. This study was the first to examine the relationship between oviductin mRNA expression and serum estradiol and luteinizing hormone and progesterone concentrations in fertile women. Estradiol and luteinizing hormone both have a stimulatory effect on oviductin mRNA in humans, however, it is difficult to determine whether ...Continue Reading

References

Apr 1, 1988·Endocrinology·H G VerhageK Donnelly
Dec 1, 1994·Cell Biology International·C D Nancarrow, J L Hill
Jul 1, 1994·Biology of Reproduction·R S King, G J Killian
Oct 28, 1997·Fertility and Sterility·L LapenséeG Bleau

❮ Previous
Next ❯

Citations

Mar 2, 2002·Fertility and Sterility·Christine Briton-JonesChristopher Haines
Mar 3, 2012·Expert Reviews in Molecular Medicine·Andrew W Horne, Hilary O D Critchley
Jun 21, 2005·Journal of Cellular and Molecular Medicine·L M PopescuCarmen Ardeleanu
Oct 8, 2005·Fertility and Sterility·Ling LingFrederick W K Kan
Sep 2, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·Yuewen ZhaoFrederick W K Kan
Jan 10, 2019·Zygote : the Biology of Gametes and Early Embryos·Gabriela Hernández-Silva, Mayel Chirinos
Jun 30, 2019·Journal of Assisted Reproduction and Genetics·Yuewen Zhao, Frederick W K Kan
Dec 23, 2020·Biomolecules·Leopoldo González-BrusiMaria Jiménez-Movilla

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.