Regulation of insect behavior via the insulin-signaling pathway

Frontiers in Physiology
Renske Erion, Amita Sehgal

Abstract

The insulin/insulin-like growth factor signaling (IIS) pathway is well-established as a critical regulator of growth and metabolic homeostasis across the animal kingdom. Insulin-like peptides (ILPs), the functional analogs of mammalian insulin, were initially discovered in the silkmoth Bombyx mori and subsequently identified in many other insect species. Initial research focused on the role of insulin signaling in metabolism, cell proliferation, development, reproduction and aging. More recently however, increasing attention has been given to the role of insulin in the regulation of neuronal function and behavior. Here we review the role of insulin signaling in two specific insect behaviors: feeding and locomotion.

Citations

Mar 4, 2015·Proceedings of the National Academy of Sciences of the United States of America·Andre KleinriddersC Ronald Kahn
May 31, 2015·Gene·James E B DochertyJustin R DiAngelo
Dec 3, 2014·Frontiers in Neuroscience·Stefanie LimmerChristian Klämbt
Jun 25, 2014·Frontiers in Physiology·Xanthe Vafopoulou
Jul 15, 2015·PloS One·Guilin R RenCornelis J P Grimmelikhuijzen
Nov 15, 2017·BMC Genomics·Elizabeth B BrownStephanie M Rollmann
Nov 6, 2018·Genome Génome / Conseil National De Recherches Canada·Baojin YaoYu Zhao
Jul 4, 2018·Nature Ecology & Evolution·Hui XiangShuai Zhan
Sep 27, 2018·G3 : Genes - Genomes - Genetics·Maria E YurgelAlex C Keene
May 31, 2019·Genes, Brain, and Behavior·Ebi A GeorgeRicarda Scheiner
Apr 21, 2018·Frontiers in Neural Circuits·Siddharth Jayakumar, Gaiti Hasan
Nov 16, 2016·ELife·Philipp SchlegelMichael J Pankratz
Jan 18, 2019·Communications Biology·Yunpeng HuangBing Zhou
Jan 17, 2021·Insect Biochemistry and Molecular Biology·Jimena LeyriaAngela B Lange
Mar 5, 2021·Proceedings of the National Academy of Sciences of the United States of America·Annika F BarberAmita Sehgal
Jan 12, 2020·Communications Biology·Yunpeng HuangBing Zhou
May 11, 2021·Frontiers in Behavioral Neuroscience·Rebecca R Westwick, Clare C Rittschof

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.