PMID: 7546406Jun 1, 1995Paper

Regulation of lymphocyte functions by nitric oxide

Current Opinion in Immunology
F Y Liew

Abstract

Current interest in nitric oxide is derived from its numerous biological roles. Immunologically, apart from the well known role of nitric oxide in anti-microbial and autoimmune diseases, nitric oxide is now emerging as a potential powerful mediator of T-cell responses. Evidence now shows that nitric oxide can both enhance and suppress T-cell functions and that some subsets of T-cell clones can be activated to produce nitric oxide.

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