PMID: 9537388Apr 16, 1998Paper

Regulation of ntcA expression and nitrite uptake in the marine Synechococcus sp. strain WH 7803

Journal of Bacteriology
D LindellAnton F Post

Abstract

NtcA is a transcriptional activator involved in global nitrogen control in cyanobacteria. In the absence of ammonium it regulates the transcription of a series of genes encoding proteins required for the uptake and assimilation of alternative nitrogen sources (I. Luque, E. Flores, and A. Herrero, EMBO J. 13:2862-2869, 1994). ntcA, present in a single copy in the marine Synechococcus sp. strain WH 7803, was cloned and sequenced. The putative amino acid sequence shows a high degree of identity to NtcA from freshwater cyanobacteria in two functional domains. The expression of ntcA was negatively regulated by ammonium from a putative transcription start point located downstream of an NtcA consensus recognition sequence. Addition of either rifampin or ammonium led to a rapid decline in ntcA transcript levels with half-lives of less than 2 min in both cases. Nitrate-grown cells showed high ntcA transcript levels, as well as the capacity for active nitrite uptake. However, ammonium-grown cells showed low levels of the ntcA transcript and did not utilize nitrite. The addition of ammonium to nitrite uptake-active cells resulted in a gradual decline in the rate of uptake over a 24-h period. Active nitrite uptake was not induced in cells ...Continue Reading

References

Mar 15, 1992·The Biochemical Journal·R RodríguezM G Guerrero
Jan 16, 1989·Biochemical and Biophysical Research Communications·M N SivakM G Guerrero
May 15, 1983·Journal of Molecular Biology·D J ShawJ R Guest
Aug 25, 1982·Nucleic Acids Research·I T WeberT A Steitz
Sep 1, 1993·Journal of Bacteriology·J E FríasE Flores
Feb 1, 1996·Journal of Bacteriology·T S RamasubramanianJ W Golden

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Citations

Dec 24, 2010·Journal of Virology·Desislava A RaytchevaJonathan A King
Aug 8, 2013·Marine Drugs·Katerina VareliIoannis Sainis
Dec 2, 2015·The ISME Journal·Shany DoronRotem Sorek
Sep 26, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Diana Gomes GradíssimoAgenor Valadares Santos
Jan 3, 2001·Journal of Bacteriology·A HerreroE Flores
Apr 17, 2016·Environmental Microbiology Reports·Shay KirznerDebbie Lindell
Jul 23, 2016·Frontiers in Microbiology·María Agustina Domínguez-MartínJosé M García-Fernández
Aug 26, 2000·Journal of Phycology·Jackie L Collier
Jul 22, 2014·Environmental Microbiology·Naama P Dekel-BirdDebbie Lindell
Oct 14, 2017·The ISME Journal·Sheila RoitmanOded Béjà
Jun 3, 2017·Viruses·Ayalla Fedida, Debbie Lindell
Nov 10, 2018·Nature Communications·Hagay EnavOded Béjà
Aug 7, 2019·Proceedings of the National Academy of Sciences of the United States of America·Sophia Zborowsky, Debbie Lindell
Apr 27, 2021·Frontiers in Microbiology·Aric H MineAlbert S Colman
Dec 22, 1999·Protein Expression and Purification·S WisénB Mannervik
Mar 6, 1999·Microbiology and Molecular Biology Reviews : MMBR·F PartenskyD Vaulot
Jun 3, 2009·Microbiology and Molecular Biology Reviews : MMBR·D J ScanlanF Partensky
Dec 14, 2004·Microbiology and Molecular Biology Reviews : MMBR·Jose Manuel García-FernándezJesús Diez
Mar 2, 2002·Applied and Environmental Microbiology·Jonathan P Zehr, Bess B Ward

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