Regulation of oxidative stress in response to acute aerobic and resistance exercise in HIV-infected subjects: a case-control study

AIDS Care
L F DereszP Dall'Ago

Abstract

Human immunodeficiency virus (HIV)-infected subjects have increased levels of oxidative stress which could impair immunological function and therefore contribute to the progression of AIDS. These characteristics are usually evaluated at rest and responses to exercise have yet to be evaluated. The aim of the present study was to assess the effect of a bout of aerobic exercise followed by resistance exercises on antioxidant system in HIV-infected and non-HIV subjects. There were included 14 cases (HIV-positive) and 14 controls (HIV-negative). The exercise protocol consisted of a single session of 20 minutes on a cycloergometer followed by a set of six resistance exercises. The activity of glutathione S-transferase (GST) and catalase were measured in plasma samples, total glutathione (TGSH) and thiobarbituric acid reactive substances (TBARS) were measured in erythrocytes. T CD4+ cells, T CD8+, viral load, complete blood count, and white blood count were also assessed. All measurements were performed at three times: baseline, after aerobic exercise, and after resistance exercises. At baseline, the HIV group had lower GST activity than controls, but after the exercise session GST values were similar in both groups. Compared to the c...Continue Reading

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Citations

Mar 13, 2014·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Xiaosha Pang, Jun Panee
Sep 30, 2018·Scandinavian Journal of Medicine & Science in Sports·Gabriella O LopesJuliana P Borges
Oct 30, 2018·HIV Clinical Trials·Luís Fernando DereszPedro Dal Lago
Mar 13, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Vitor H F OliveiraRafael Deminice
Mar 21, 2019·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Christopher McGrewDouglas McKeag
Mar 21, 2019·British Journal of Sports Medicine·Christopher McGrewDouglas McKeag
Sep 19, 2019·Journal of Physical Activity & Health·Bruno P MeloSolange M Franzói de Moraes

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