Regulation of specific genes during the cell cycle. Utilization of homologous cDNAs and cloned sequences for studying histone gene expression in human cells

Cell Biophysics
G SteinL F Sierra

Abstract

Evidence for differential gene expression during the cell cycle and approaches for studying cell-cycle-stage specific gene expression are summarized. Attention is focused on regulation of histone gene expression during the cell cycle of continuously dividing cells and after stimulation of nondividing cells to proliferate. The level(s) at which control of histone gene expression occurs and the possible involvement of chromosomal proteins in the regulation of histone gene expression are discussed. The preparation of cloned human histone sequences and their use in studying the structural and functional properties of human histone genes are presented. Index Entries: Cell cycle, gene regulation during; gene regulation, during the cell cycle; regulation of specific genes, during the cell cycle; DNAs, homologous, and histone gene expression; cloned DNAs, and histone gene expression; histone gene expression; gene expression, histone; cloned human histone sequences.

References

Apr 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·L J KleinsmithG Stein
Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M RossiniR Baserga
Jan 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·R L JansingG S Stein
Jan 1, 1978·Cold Spring Harbor Symposia on Quantitative Biology·G S SteinI R Phillips
Jun 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·L M Wiedemann, L F Johnson
Oct 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·S DetkeG Stein
Jan 1, 1978·Annual Review of Biochemistry·A B PardeeR F Kletzien
May 17, 1977·Biochemistry·J L SteinP M McGuire
Oct 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·M Grunstein, D S Hogness
Mar 1, 1974·Science·G S SteinL J Kleinsmith
Aug 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·M Jacobs-LorenaT W Borun
Oct 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·A Skoultchi, P R Gross
Jan 1, 1972·Advances in Cancer Research·G Stein, R Baserga
Sep 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·K W GrossP R Gross
Nov 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·J SpaldingG C Mueller
Nov 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·T W BorunE Robbins
Feb 1, 1980·Cell Differentiation·I Parker, W Fitschen
Jul 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·R C HUANG, J BONNER
Feb 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·E Robbins, T W Borun

❮ Previous
Next ❯

Citations

Feb 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·R RicklesG Stein
Aug 1, 1992·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·J ShavilaD V Parke
Nov 4, 2009·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Lamia AbbasNicolas Glade

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.