PMID: 11934613Apr 6, 2002Paper

Regulation of type III secretion systems

Current Opinion in Microbiology
M S FrancisAke Forsberg

Abstract

Type III secretion systems are utilised by numerous Gram-negative bacteria to efficiently interact with a host. Appropriate expression of type III genes is achieved through the integration of several regulatory pathways that ultimately co-ordinate the activity of a central transcriptional activator usually belonging to the AraC family. The complex regulatory cascades allow this virulence strategy to be utilised by different bacteria even if they occupy diverse niches that define a unique set of environmental cues. Simulating the appropriate combination of signals in vitro to allow a meaningful interpretation of the type III assembly and secretion regulatory cascade remains a common goal for researchers. Pieces of the puzzle slowly emerge to provide insightful views into the complex regulatory networks that allow bacteria to assemble and utilise type III secretion to efficiently colonise a host.

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Citations

Mar 7, 2003·FEMS Microbiology Letters·Mario F Feldman, Guy R Cornelis
Nov 1, 2006·Molecular Plant-microbe Interactions : MPMI·Xiaoyan TangJian-Min Zhou
Aug 18, 2009·Applied and Environmental Microbiology·Silvia VilchesSusana Merino
Sep 21, 2010·Journal of Bacteriology·Cindy J Gode-PotratzLinda L McCarter
Jul 3, 2004·Journal of Bacteriology·Alireza Shamaei-TousiGad Frankel
Dec 14, 2004·Microbiology and Molecular Biology Reviews : MMBR·Partho Ghosh
Apr 26, 2005·Annual Review of Microbiology·Gloria I Viboud, James B Bliska
Jul 31, 2004·Annual Review of Phytopathology·James R Alfano, Alan Collmer
Jun 30, 2005·Proceedings of the National Academy of Sciences of the United States of America·Mark L UrbanowskiTimothy L Yahr
Feb 1, 2013·Journal of Biomolecular Screening·Jeff M SkredenskeSusan M Egan
Apr 9, 2008·Current Opinion in Microbiology·Evan D Brutinel, Timothy L Yahr
Jul 14, 2007·Trends in Microbiology·Beth M MoleSarah R Grant
Jul 28, 2005·Protein Science : a Publication of the Protein Society·Carina R BüttnerHartmut H Niemann
Oct 8, 2004·Molecular Microbiology·Gregory V Plano
Oct 25, 2011·Molecular Microbiology·Julie M SilvermanJoseph D Mougous

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