Regulatory aspects of cellulase biosynthesis and secretion

Critical Reviews in Biotechnology
V S Bisaria, S Mishra

Abstract

The cellulase enzyme system consists of cellobiohydrolase, endoglucanase, and beta-glucosidase and has been extensively studied with respect to its biosynthesis, properties, mode of action, application, and, most recently, secretion mechanisms. A knowledge of the factors governing the biosynthesis and secretion of these enzymes at the molecular level will be useful in maximizing enzyme productivity in extracellular fluid. Among other topics, the regulatory effects of sorbose (a noninducing sugar which is not a product of cellulose hydrolysis) on cellulase synthesis and release are described. Cellulase genes have recently been cloned into a number of microorganisms with a view to understanding the gene structure and expression and to obtaining the enzyme components in pure form. The factors governing biosynthesis and secretion of cellulases in recombinant cells are also discussed. Cellulases are known to be glycoproteins, therefore, the role of O- and N-linked glycosylation on enzyme stability and secretion is also detailed.

References

May 1, 1976·Applied and Environmental Microbiology·D Sternberg
Apr 1, 1978·Applied and Environmental Microbiology·F Bissett, D Sternberg
Jun 1, 1979·Canadian Journal of Microbiology·J G Shewale, J C Sadana
Sep 1, 1979·Journal of Bacteriology·D Sternberg, G R Mandels
Jan 1, 1979·Annual Review of Genetics·M Rosenberg, D Court
Jan 1, 1979·Biotechnology and Bioengineering·T K Ghose, V S Bisaria
Aug 1, 1977·Carbohydrate Research·T M Wood, S I McCrae
Mar 1, 1978·The Biochemical Journal·G Halliwell, M Griffin
Feb 1, 1977·The Journal of Applied Bacteriology·B Berg, G Pettersson
Jul 1, 1977·Biotechnology and Bioengineering·C S GongG T Tsao
May 13, 1977·Archives of Microbiology·J R Loewenberg, C M Chapman
Jan 1, 1978·Applied and Environmental Microbiology·K M Nevalainen, E T Palva
Mar 14, 1978·Biochimica Et Biophysica Acta·S P Shoemaker, R D Brown
Mar 14, 1978·Biochimica Et Biophysica Acta·S P Shoemaker, R D Brown
Feb 15, 1979·FEBS Letters·L G Fägerstam, L G Pettersson
Oct 31, 1979·Journal of Chromatography·F H Bissett
Sep 15, 1978·European Journal of Biochemistry·K E Eriksson, S G Hamp
Nov 1, 1976·Journal of Bacteriology·B J Stewart, J M Leatherwood
Feb 1, 1977·Canadian Journal of Microbiology·D SternbergE T Reese
Mar 1, 1977·Comprehensive Psychiatry·M R Lansky
Dec 1, 1976·The Journal of Applied Bacteriology·B Berg, A V Hofsten
Apr 1, 1985·Biochemical Society Transactions·M Mandels
Jul 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·Y Nagamine, E Reich
Sep 11, 1985·Nucleic Acids Research·C Kohchi, A Toh-e
Feb 1, 1986·Molecular & General Genetics : MGG·P BéguinJ P Aubert
Nov 25, 1986·Nucleic Acids Research·R M MacKayV Seligy
Apr 15, 1987·European Journal of Biochemistry·A NakamuraT Beppu
May 1, 1987·Journal of Bacteriology·L M Robson, G H Chambliss

❮ Previous
Next ❯

Citations

Feb 1, 1993·Current Genetics·H StanglC P Kubicek
Nov 3, 2010·Applied Biochemistry and Biotechnology·Roopa K GaonkarM A Vijayalakshmi
Jan 1, 1991·Journal of Biotechnology·J M UusitaloM E Penttilä
Jan 1, 1994·FEMS Microbiology Reviews·P Béguin, J P Aubert
Jun 24, 2003·Biochimica Et Biophysica Acta·Anu Wallecha, Saroj Mishra
Jan 7, 2003·Applied and Environmental Microbiology·Nina AroMerja Penttilä
Aug 29, 2013·BioMed Research International·Pragya TiwariNeelam S Sangwan
Jan 6, 2011·Critical Reviews in Biotechnology·Anjali MadhavanVirendra S Bisaria
Dec 19, 2002·Critical Reviews in Biotechnology·Yukti BhatiaV S Bisaria
Apr 15, 2016·Bioscience, Biotechnology, and Biochemistry·Yosuke ShidaWataru Ogasawara
Aug 17, 2005·FEMS Microbiology Reviews·Nina AroMerja Penttilä
Aug 26, 2014·Frontiers in Chemistry·Mohammad M RahmanTakao Ojima
Nov 4, 2004·FEMS Microbiology Letters·Fabiana Fonseca ZanoeloJoão Atílio Jorge
May 3, 2014·Archives of Insect Biochemistry and Physiology·Hatibe Ertürk KaraSelma Sinan
Jun 11, 1999·Molecular Microbiology·C M SzymanskiP Guerry
Dec 21, 2019·World Journal of Microbiology & Biotechnology·Habib BokhariAbdul Rauf Siddiqi
Jun 17, 1998·Applied Biochemistry and Biotechnology·A SachslehnerK D Kulbe
Jun 1, 2017·Journal, Genetic Engineering & Biotechnology·B C BeheraH N Thatoi
Jun 23, 2009·Biochemistry. Biokhimii︠a︡·O G KorotkovaA P Sinitsyn
Dec 14, 2005·Applied and Environmental Microbiology·A SachslehnerD Haltrich

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.