Rehabilitation after cell transplantation for cartilage defects

Transplantation Proceedings
J Deszczynski, K Slynarski

Abstract

Rehabilitation is a key element of successful treatment of cartilage defects with cell transplantation. The process of graft maturation takes approximately 18 months and cannot be accelerated, but requires carefully introduced steps leading to early recovery of joint function. Rehabilitation starts at 8 hours after surgery with the continuous passive motion (CPM) exercises and physiotherapy. For the first 6 weeks, patients continue with CPM in the range of 0 degrees to 45 degrees for femoral and tibial defects and 0 degrees to 30 degrees for patellofemoral joint reconstruction. Isometric muscle training and scar manual therapy are introduced. Patients are allowed to weight-bear as tolerated from the second week after surgery. After this initial phase, from 6 to 8 weeks after surgery, rehabilitation is accelerated with increased load-bearing and progressive range of motion to full flexion. Usually patients are able to walk without crutches in this time. Proprioceptive training is introduced with the advance of pain-free full range of motion and no discomfort with full weight-bearing. At 6 months after surgery, most patients recover joint function, making it possible for them to return to daily living activities. However, they ne...Continue Reading

References

Oct 6, 1994·The New England Journal of Medicine·M BrittbergL Peterson
Apr 1, 1997·Acta Orthopaedica Scandinavica·M BrittbergL Peterson
Oct 24, 1998·The Journal of Orthopaedic and Sports Physical Therapy·J A Buckwalter
Oct 24, 1998·The Journal of Orthopaedic and Sports Physical Therapy·J J Irrgang, D Pezzullo
Aug 26, 1999·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·H Alfredson, R Lorentzon
Oct 18, 2001·Clinical Orthopaedics and Related Research·L A SolchagaA I Caplan
Oct 18, 2001·Clinical Orthopaedics and Related Research·J R SteadmanJ J Rodrigo
Mar 7, 2002·Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique·H Robert
Feb 11, 2005·The American Journal of Sports Medicine·J Winslow Alford, Brian J Cole
Mar 8, 2005·Orthopedics·Bert Mandelbaum, David Waddell

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Citations

Nov 4, 2011·Journal of Shoulder and Elbow Surgery·Stefan BuchmannAndreas B Imhoff
Apr 27, 2013·The American Journal of Sports Medicine·Jay R EbertTimothy R Ackland
Jan 19, 2021·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Jay R EbertGregory C Janes

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