PMID: 22568097May 10, 2012Paper

Rehabilitation medicine, laboratory medicine, and hypertension--my 38-year academic career in Tohoku University and Hirosaki University

Rinsho byori. The Japanese journal of clinical pathology
Minoru Yasujima

Abstract

Hypertension is a major contributor to the risks for cardiovascular diseases. The cause of approximately 90% of hypertension cases is unknown, despite decades of research and debate. Many factors including renal mechanisms and the renin-angiotensin system are involved in the regulatory mechanisms of blood pressure. Genetic and environmental factors interact to affect multiple factors related to hypertensive mechanisms. Recent data suggested that genetic risk factors have been useful in clinical practice. The evidence that treatment of hypertension reduces cardiovascular diseases come from the results of large-scale therapeutic trials. Significant progress has been made during the last several decades in the treatment of hypertension through the use of inhibitors of the renin-angiotensin system, with either angiotensin converting enzyme inhibitors or angiotensin receptor type 1 blockers. In this review, I summarize my personal career related to hypertension research.

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.