Rehmannia glutinosa: review of botany, chemistry and pharmacology

Journal of Ethnopharmacology
Ruxue ZhangZhengping Jia

Abstract

Rehmannia glutinosa, a widely used traditional Chinese herb, belongs to the family of Scrophulariaceae, and is taken to nourish Yin and invigorate the kidney in traditional Chinese medicine (TCM) and has a very high medicinal value. In recent decades, a great number of chemical and pharmacological studies have been done on Rehmannia glutinosa. More than 70 compounds including iridoids, saccharides, amino acid, inorganic ions, as well as other trace elements have been found in the herb. Studies show that Rehmannia glutinosa and its active principles possess wide pharmacological actions on the blood system, immune system, endocrine system, cardiovascular system and the nervous system. Currently, the effective monomeric compounds or active parts have been screened for the pharmacological activity of Rehmannia glutinosa and the highest quality scientific data is delivered to support the further application and exploitation for new drug development.

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Citations

Jan 6, 2011·Diabetes, Obesity & Metabolism·W Xie, L Du
Oct 31, 2012·Journal of Periodontology·Bo-Ah LeeYoung-Joon Kim
Dec 4, 2012·International Journal of Molecular Sciences·Peng SunXianen Li
Jan 2, 2014·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Ruxue ZhangZhengping Jia
May 21, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dong Wook Lim, Yun Tai Kim
Feb 24, 2016·Drug Discoveries & Therapeutics·Yasuhiko Matsumoto, Kazuhisa Sekimizu
May 12, 2009·Journal of Ethnopharmacology·Di ZhangYu Zhao
Jan 17, 2009·Journal of Ethnopharmacology·Byung-Cheol LeeYoung-Seung Kim
Sep 6, 2015·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Bingyang XueZimei Wu
Jan 11, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Soon Re KimSeong-Gyu Ko
Jul 24, 2013·Journal of Ethnopharmacology·C LauI Meijerman
Dec 8, 2010·Journal of Ethnopharmacology·Pathirage Kamal PereraCaifeng Han
Sep 13, 2014·Journal of Chromatographic Science·Shengqiang TongYoichiro Ito
Dec 19, 2012·International Journal of Biological Macromolecules·Zhenjie ZhangFengping Shan
Dec 24, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Jang Su JeonSang Kyum Kim
Jul 18, 2016·BMC Complementary and Alternative Medicine·Min Kyoung KimSe Young Choung
Oct 25, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·In-Seung LeeHyeung-Jin Jang
Aug 24, 2016·BMC Complementary and Alternative Medicine·Kang Pa LeeWon-Hwan Park

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