Abstract
Two patients with reinfection of Borrelia burgdorferi are presented. An 11-year-old girl developed recurrent acute peripheral facial palsy at an interval of five years. A 64-year-old woman showed paraesthesia in the leg and effusion in the knee. Three years later, an erythema migrans developed at the thigh. In both patients tick bites, corresponding clinical manifestations, and detection of specific antibodies proved the reinfections. The course of the humoral immune responses showed basic differences between the patients. At the interval between the first and second infection, the specific antibodies of the girl decreased beyond the cut-off level. On the other hand, the titer of specific IgG antibodies of the other patient remained at a constant level. Reasons for the failure of immune protection are discussed.
References
Jul 1, 1992·International Journal of Systematic Bacteriology·G BarantonP A Grimont
May 1, 1992·Infection and Immunity·H EiffertR Thomssen
Jan 1, 1991·Scandinavian Journal of Infectious Diseases·H EiffertR Thomssen
Aug 31, 1989·The New England Journal of Medicine·A C Steere
Oct 25, 1986·Lancet·H W PfisterG D Borasio
Oct 1, 1988·The Journal of Infectious Diseases·V P BerardiA C Steere
Feb 1, 1987·Zentralblatt Für Bakteriologie, Mikrobiologie, Und Hygiene. Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology·P MünchhoffG Schierz
Oct 1, 1986·The Journal of Clinical Investigation·J E CraftA C Steere
Feb 1, 1986·The Journal of Infectious Diseases·B WilskeK Einhäupl
Jan 1, 1986·Infection·K WeberW Burgdorfer
Sep 1, 1984·Infection·B WilskeK Einhäupl
Jun 18, 1982·Science·W BurgdorferJ P Davis
Jun 1, 1995·Infection and Immunity·S D LovrichR F Schell
Feb 1, 1995·The Journal of Infectious Diseases·H EiffertF R Matuschka
Mar 11, 1994·Deutsche medizinische Wochenschrift·D Hassler, M Maiwald
Feb 1, 1993·Journal of Clinical Microbiology·B WilskeG Zumstein
Feb 1, 1993·Acta Paediatrica. Supplement·H J ChristenR Thomssen
Citations
Sep 21, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert B Nadelman, Gary P Wormser
Aug 23, 2008·Scandinavian Journal of Infectious Diseases·Niels V KrabbeHenrik Nielsen
Sep 6, 2011·Ticks and Tick-borne Diseases·Delphine HuegliLise Gern
Mar 16, 2007·Médecine et maladies infectieuses·V Remy
May 17, 2017·Survey of Ophthalmology·Radgonde AmerNilüfer Yalçındağ
Oct 10, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gary P WormserRobert B Nadelman
Jun 9, 2005·Parasitology·J Piesman, L Gern
Jun 27, 2018·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Pegah TouradjiKathleen T Bechtold
Nov 13, 2018·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·John G KeilpBrian A Fallon
Oct 18, 2011·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·R EikelandG C Løhaugen
Jun 14, 2012·Acta Neurologica Scandinavica·R EikelandU Ljøstad
Feb 24, 2019·Neurology·Anneleen BerendeBart Jan Kullberg
Oct 23, 2016·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Roberta Carvalho BasileAntonio de Queiroz-Neto
Apr 3, 2018·Critical Reviews in Clinical Laboratory Sciences·Benedikt LohrKlaus-Peter Hunfeld
Dec 8, 2005·CNS Drugs·Göran Günther, Mats Haglund