Reinstatement of memory representations for lifelike events over the course of a week

Scientific Reports
Christiane S H OedekovenChris M Bird

Abstract

When we remember an event, the content of that memory is represented across the brain. Detailed memory retrieval is thought to involve the reinstatement of those representations. Functional MRI combined with representational similarity analyses (RSA) of spatial patterns of brain activity has revealed reinstatement of recently-experienced events throughout a core memory retrieval network. In the present study, participants were scanned while they watched, immediately retrieved and then retrieved after a week, 24 short videos. Following the delayed retrieval, they freely recalled all videos outside of the scanner. We observed widespread within- and between-subject reinstatement effects within a posterior midline core memory retrieval network during all phases of the experiment. Within precuneus, bilateral middle temporal gyrus and the left hippocampus, reinstatement effects between the retrieval phases correlated with memory performance. These findings extend previous studies that have only employed short retention periods or highly rehearsed materials, demonstrating that memory representations for unique events are reliably reinstated over longer timeframes that are meaningful in the context of real-world episodic memory.

References

Nov 3, 1970·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·D Marr
Jul 19, 1994·Proceedings of the National Academy of Sciences of the United States of America·P Alvarez, L R Squire
Apr 1, 1997·Current Opinion in Neurobiology·L Nadel, M Moscovitch
Sep 27, 2000·Proceedings of the National Academy of Sciences of the United States of America·L NybergE Tulving
Sep 27, 2000·Proceedings of the National Academy of Sciences of the United States of America·M E WheelerR L Buckner
Dec 26, 2001·Annual Review of Psychology·Endel Tulving
Jan 1, 2003·Psychology and Aging·Brian LevineMorris Moscovitch
Apr 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Mar 2, 2006·Psychological Science·Henry L Roediger, Jeffrey D Karpicke
Jun 16, 2009·Neuropsychologia·Martin A Conway
Jan 14, 2010·Neuromolecular Medicine·Reisa A SperlingKeith A Johnson
Mar 17, 2010·Current Biology : CB·Martin J ChadwickEleanor A Maguire
Oct 16, 2010·Science·Mary A Pyc, Katherine A Rawson
Oct 19, 2010·Trends in Cognitive Sciences·Henry L Roediger, Andrew C Butler
Jul 7, 2011·Journal of the International Neuropsychological Society : JINS·Gordon Winocur, Morris Moscovitch
May 30, 2012·Journal of Cognitive Neuroscience·Bradley R BuchsbaumHervé Abdi
Sep 21, 2012·Nature Reviews. Neuroscience·Charan Ranganath, Maureen Ritchey
Nov 28, 2012·Neuron·Daniel L SchacterKarl K Szpunar
Dec 5, 2012·Current Opinion in Neurobiology·Michael D Rugg, Kaia L Vilberg
Dec 15, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Bernhard P StaresinaArjen Alink
Jun 6, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Brice A Kuhl, Marvin M Chun
Jun 24, 2015·Journal of Cognitive Neuroscience·Marie St-LaurentBradley R Buchsbaum
Aug 9, 2016·Frontiers in Neuroinformatics·Nikolaas N OosterhofJames V Haxby
Dec 6, 2016·Nature Neuroscience·Janice ChenUri Hasson
Feb 17, 2017·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xiaoqian XiaoGui Xue
Jun 7, 2017·Trends in Cognitive Sciences·James W AntonyMaria Wimber

❮ Previous
Next ❯

Citations

Sep 6, 2019·Topics in Cognitive Science·David StawarczykJeffrey M Zacks
Mar 13, 2020·Journal of Cognitive Neuroscience·Arnaud D'Argembeau
Dec 18, 2019·Behavior Research Methods·Rosalie SamideMaureen Ritchey
Jul 28, 2020·Neuroscience and Biobehavioral Reviews·Iva K BrunecMorgan D Barense
Jan 16, 2021·Sleep Health·Zlatan Krizan, Garrett Hisler
Jan 17, 2020·Neuropsychologia·Arne D Ekstrom, Andrew P Yonelinas
Apr 29, 2020·Trends in Cognitive Sciences·Maureen Ritchey, Rose A Cooper
Feb 24, 2021·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Adrien FolvilleChristine Bastin
Dec 24, 2021·Journal of Cognitive Neuroscience·Konstantinos BromisChris M Bird

❮ Previous
Next ❯

Methods Mentioned

BETA
RSA
RSAs

Software Mentioned

Cogent
MATLAB
Enc
searchlight
ImRet
Anatomy SPM8
CoSMoMVPA
SPM8
RSA
DelRet

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.