PMID: 11325440Apr 28, 2001Paper

Reirradiation of primary brain tumours: survival, clinical response and prognostic factors

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
T VeningaR W van der Maazen

Abstract

First, the aim was to determine the survival and quality of life after reirradiation of relapsing primary malignant brain tumours. The second aim was to assess the influence of a set of potentially prognostic factors on survival. Forty-two patients received reirradiation for recurring primary brain tumours. The interval between the two consecutive treatments was at least 1 year. External beam irradiation for the initial and recurrent tumour was usually delivered with two opposing lateral fields or two wedged fields in orthogonal directions. The median physical doses of the first and second radiation course were 50 and 46 Gy, respectively. The median cumulative biological equivalent doses (BED) were 200.4 (alpha/beta = 2 Gy) and 115.2 Gy (alpha/beta = 10 Gy). During follow-up, corticosteroid medication and the WHO-performance were registered at regular intervals. The radiological response was assessed by reviewing all available CT- and MRI-films. Potentially prognostic factors with respect to survival were evaluated by both univariate and multivariate analyses. A clinical response (i.e. clinical improvement) was seen in 24% of the patients. Of the evaluable patients, nearly one-third showed a complete (8%) or partial (22%) radio...Continue Reading

References

Feb 1, 1992·Journal of Neuro-oncology·D L SilbergeldG A Ojemann
Oct 1, 1990·International Journal of Radiation Oncology, Biology, Physics·T E SchultheissL J Peters
Jun 1, 1989·International Journal of Radiation Oncology, Biology, Physics·K E WallnerM G Malkin
Nov 1, 1987·Neurosurgery·G R HarshC B Wilson
Aug 1, 1988·International Journal of Radiation Oncology, Biology, Physics·M B Hazuka, J J Kinzie
Nov 15, 1988·Cancer·C Daumas-DuportP Kelly
Jan 1, 1985·Journal of Neuro-oncology·J van EysB Smith
Feb 1, 1981·International Journal of Radiation Oncology, Biology, Physics·J E MarksW F Blank
Dec 1, 1981·Journal of Neurosurgery·B YoungW F Meacham
Dec 1, 1983·Cancer·M T SmithV W Armbrustmacher
Sep 1, 1980·International Journal of Radiation Oncology, Biology, Physics·G E ShelineV Smith
Jan 1, 1981·Cancer·A B MillerA Winkler
Mar 30, 1995·International Journal of Radiation Oncology, Biology, Physics·T E SchultheissL C Stephens
Jun 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·F MornexL Taillandier
Jul 1, 1993·Brain Pathology·P KleihuesB W Scheithauer
Feb 15, 1993·International Journal of Radiation Oncology, Biology, Physics·K K AngL J Peters
Feb 1, 1996·International Journal of Radiation Oncology, Biology, Physics·W W WongE G Shaw
Sep 1, 1996·International Journal of Radiation Oncology, Biology, Physics·G S BaumanD A Larson
Oct 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E SalminenS Huhtala
Jan 15, 1997·International Journal of Radiation Oncology, Biology, Physics·S F ShepherdM Brada
Feb 25, 1999·International Journal of Radiation Oncology, Biology, Physics·R S HudesW J Curran
Mar 31, 1999·International Journal of Radiation Oncology, Biology, Physics·M ArcicasaM G Trovò
Dec 29, 1999·International Journal of Radiation Oncology, Biology, Physics·K H ChoH B Clark
Jan 7, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J LutterbachW Hinkelbein
Jan 7, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·U OppitzM Flentje

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Citations

Nov 2, 2002·Journal of Magnetic Resonance Imaging : JMRI·Jeff F DunnHarold M Swartz
Apr 11, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sei Hwan YouChang-Ok Suh
Feb 12, 2011·Wiener medizinische Wochenschrift·Dietmar Seewald
Oct 13, 2006·Current Treatment Options in Oncology·Lyndon Kim, Michael Glantz
Jun 14, 2002·International Journal of Radiation Oncology, Biology, Physics·Ajay BhatnagarJohn C Flickinger
Jun 6, 2008·American Journal of Clinical Oncology·Carsten NiederMichael Molls
Nov 2, 2011·Journal of Pediatric Hematology/oncology·Laetitia PadovaniXavier Muracciole
Sep 1, 2007·BMC Cancer·Stephanie E CombsDaniela Schulz-Ertner
Mar 19, 2013·Journal of Medical Case Reports·Michela BuglioneStefano Maria Magrini
Aug 10, 2010·Core Evidence·Ayman I Omar, Warren P Mason
Oct 11, 2005·Neurosurgical Focus·Herbert H Engelhard
Feb 26, 2009·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Guido HenkeClaus Belka
Oct 5, 2010·Clinical Oncology : a Journal of the Royal College of Radiologists·K JosephW Levin
May 18, 2010·International Journal of Radiation Oncology, Biology, Physics·Jarrod B AdkisonSteven P Howard
Feb 12, 2008·International Journal of Radiation Oncology, Biology, Physics·Arnold C PaulinoBin S Teh
Nov 27, 2007·International Journal of Radiation Oncology, Biology, Physics·Ramona Mayer, Peter Sminia
Jul 31, 2007·Clinical Oncology : a Journal of the Royal College of Radiologists·E SadikovN Laperriere
Nov 27, 2015·PM & R : the Journal of Injury, Function, and Rehabilitation·Vishwa S RajMichael W O'Dell
Oct 20, 2005·European Journal of Radiology·Heikki Minn
Jan 18, 2011·International Journal of Radiation Oncology, Biology, Physics·Malika L SikerChristopher J Schultz
Mar 10, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nicholas A ButowskiSusan M Chang
Nov 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephanie E CombsDaniela Schulz-Ertner
Jun 30, 2016·Technology in Cancer Research & Treatment·Melis GultekinMurat Gurkaynak
Oct 22, 2004·Seminars in Oncology·Stuart A Grossman, Julette F Batara
Jan 1, 2011·Cancers·Maurizio Amichetti, Dante Amelio
Jan 1, 2012·Cancers·Dante Amelio, Maurizio Amichetti
May 18, 2016·Yonsei Medical Journal·Jeongshim LeeChang Ok Suh
Jan 18, 2012·Journal of Neuro-oncology·Stephan DützmannChristian Senft
Jul 3, 2019·The British Journal of Radiology·Robert PoelRobert Foerster
Dec 14, 2019·Journal of Applied Clinical Medical Physics·Yuan XuJianrong Dai
Jan 15, 2013·Journal of Neuro-oncology·Thomas HundsbergerLudwig Plasswilm
Dec 25, 2015·Journal of Applied Clinical Medical Physics·Marie HussIuliana Toma-Dasu
Jul 1, 2016·International Journal of Particle Therapy·Benjamin FarniaSusan L McGovern
Sep 25, 2008·Journal of Neuro-oncology·Shin-Ichi MiyatakeKoji Ono
Dec 12, 2020·Critical Reviews in Oncology/hematology·Silvia ScocciantiLorenzo Livi
Jan 1, 2011·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Marzanna ChojnackaDanuta Perek

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