Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus

Journal of Menopausal Medicine
Seok Hwan KimTae Hee Kim

Abstract

Vaginal atrophy is a common condition among peri- and post-menopausal women. Symptoms of vaginal dryness, pruritus, irritation, loss of subcutaneous fat, sparse pubic hair and dyspareunia occur due to decreased estrogen level. Estrogen-based treatments are effective. But many patients are reluctant to be treated due to health concerns. As alternatives, we explored the efficacy of platelet-rich plasma (PRP) and lipofilling. A 67-year-old female patient with vaginal atrophy was referred to our department. Treatment using estrogen cream had failed to improve patient's symptoms. Diminished volume and aged look of genitalia were also major concerns. We treated her using lipofilling mixed with PRP. A total of 40 cc of autologous fat mixed with PRP was transferred to labia majora. Lipofilling with PRP relieved the clinical symptoms. Missing fullness and tone was corrected and the augmented volume was well maintained. White patchy lesions of lichen sclerosus on labia minora also improved. Lipofilling with PRP relieved symptoms, restored contour of the labia majora and achieved remission of lichen sclerosus on labia minora. As vulvar lesions were repaired and the aged appearance of genitalia was rejuvenated, both functional and cosmetic...Continue Reading

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Citations

Sep 28, 2017·Journal of Menopausal Medicine·Jae Jun ShinChang Suk Suh
May 10, 2020·Aesthetic Surgery Journal·Sophie MenkesBarbara Hersant
Jul 10, 2018·Clinical and Experimental Reproductive Medicine·Ayman Shehata Dawood, Hesham Abdelaziz Salem
Apr 24, 2020·Drug Delivery and Translational Research·Sarah M KolaViness Pillay
May 14, 2019·Journal of Menopausal Medicine·Peter TakacsRobert Poka
Dec 1, 2020·Platelets·Paula Oneto, Julia Etulain
Dec 3, 2020·Deutsches Ärzteblatt International·Linn Wölber
Mar 3, 2021·Aesthetic Plastic Surgery·Zhifang ZhengWenhua Huang
Apr 29, 2021·Surgical Innovation·Anastasia ProdromidouThemos Grigoriadis
Aug 11, 2021·Aesthetic Plastic Surgery·Bulent CihantimurYavuz Ozsular

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Methods Mentioned

BETA
hormone replacement therapy
biopsy

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