Relapses of inflammatory bowel disease during pregnancy: in-hospital management and birth outcomes

The American Journal of Gastroenterology
Deepa ReddyAsher A Kornbluth

Abstract

There are few studies that describe the medical treatment and colitis response rates among patients with a severe relapse of inflammatory bowel disease (IBD) during pregnancy, and few studies of the effect of such a relapse on birth outcomes in these patients. To describe the treatment and response rates of severe colitis in pregnancy, and to assess the effects of a severe relapse of colitis during pregnancy on birth outcomes. We performed a case control study of pregnant patients with IBD hospitalized for a disease relapse at two large treatment centers between 1989 and 2001. Details of management of disease relapse and maternal and fetal outcomes were recorded. Eighteen patients (11 ulcerative colitis, 6 Crohn's disease, 1 indeterminate colitis), mean age 28.6 yr (range 19-38) formed the study group; 41 age-matched pregnant IBD patients without disease relapse formed the control group. Study patients were hospitalized at a mean of 15.9-wk gestation (range 8-35) for a mean of 10.4 days (range 3-31). All 18 patients received IV hydrocortisone (mean dose 199 mg/day) and 7 patients (39%) either continued taking or were commenced on immunomodulators: IV cyclosporine (5 patients) and azathioprine/6-MP (3 patients). Fifteen patients...Continue Reading

References

Apr 1, 1989·American Journal of Obstetrics and Gynecology·D M FedorkowC A Nimrod
Apr 1, 1986·Journal of the Royal Society of Medicine·J P Miller
Feb 1, 1981·Prostaglandins and Medicine·S R GouldJ E Lennard-Jones
Sep 1, 1983·Scandinavian Journal of Gastroenterology·O H NielsenS Jarnum
Nov 25, 1997·American Journal of Obstetrics and Gynecology·D KornfeldA Ekbom
Dec 22, 1998·The American Journal of Gastroenterology·K FonagerS N Rasmussen
Apr 14, 2000·The American Journal of Gastroenterology·M A MoserR J Bailey
Nov 30, 2000·The American Journal of Gastroenterology·B NørgårdJ Olsen
Apr 3, 2002·The American Journal of Gastroenterology·Jason A DominitzEdward J Boyko
Sep 23, 2003·The American Journal of Gastroenterology·Bente NørgårdHenrik T Sørensen
Jul 29, 2004·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·M C BushJ L Stone
Aug 13, 2004·Gut·A JayaprakashH A Shehata
Jul 27, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Gabby ElbazEyal Sheiner
Oct 7, 2005·Journal de gynécologie, obstétrique et biologie de la reproduction·A BeniadaM Dreyfus
May 31, 2006·Gastroenterología y hepatología·E Ubiña-AznarE Perea-Milla

❮ Previous
Next ❯

Citations

Jul 31, 2013·Nature Reviews. Gastroenterology & Hepatology·Ole Haagen NielsenJakob Hendel
Apr 8, 2014·World Journal of Gastroenterology : WJG·Vivian W Huang, Flavio M Habal
Oct 28, 2015·Journal of Crohn's & Colitis·Sophie A van den BergNanne K H de Boer
Mar 17, 2016·Expert Review of Clinical Immunology·Jill K J Gaidos, Sunanda V Kane
Nov 15, 2012·Blood·Terry GernsheimerRoberto Stasi
Jan 21, 2015·Journal of Crohn's & Colitis·C J van der WoudeUNKNOWN European Crohn’s and Colitis Organization
Jun 29, 2016·The American Journal of Gastroenterology·Alison de Lima-KaragiannisChristien Janneke van der Woude
Mar 15, 2014·Current Opinion in Rheumatology·Benjamin Hassid, Uma Mahadevan
Feb 10, 2017·Current Treatment Options in Gastroenterology·Jill K J Gaidos, Sunanda V Kane
Nov 5, 2015·United European Gastroenterology Journal·Soleiman B KashkooliRupert W Leong
Dec 15, 2015·Inflammatory Bowel Diseases·Rachel WinterSonia Friedman
Oct 8, 2015·Inflammatory Bowel Diseases·Ryan A McConnell, Uma Mahadevan
Jan 13, 2009·Inflammatory Bowel Diseases·Julien BrancheJean-Frédéric Colombel
May 5, 2018·Journal of Crohn's & Colitis·Alison de LimaC Janneke van der Woude
Nov 12, 2015·World Journal of Gastrointestinal Pharmacology and Therapeutics·Pegah Hosseini-CarrollJonathan Steven Alexander
May 14, 2016·Intestinal research·Shunsuke KomotoUNKNOWN Japanese study group for pregnant women with IBD
Feb 10, 2011·Nature Reviews. Gastroenterology & Hepatology·Barrett G Levesque, Sunanda V Kane
Dec 19, 2012·Nature Reviews. Gastroenterology & Hepatology·Ole Haagen Nielsen, Tine Jess
May 18, 2018·Journal of Crohn's & Colitis·Shannon L KanisC Janneke van der Woude
May 23, 2018·Inflammatory Bowel Diseases·Benjamin KoslowskyAriella Bar-Gil Shitrit
Jul 2, 2015·Intestinal research·Kang-Moon LeeUNKNOWN IBD Study Group of the Korean Association for the Study of Intestinal Diseases
Dec 3, 2010·Journal of Crohn's & Colitis·C Janneke van der WoudeUNKNOWN European Crohn's Colitis Organisation (ECCO)
Mar 6, 2013·The American Journal of Gastroenterology·Sarah Sheibani, Uma Mahadevan
Sep 22, 2009·Current Gastroenterology Reports·Maria Moscandrew, Sunanda Kane
Nov 12, 2009·Current Gastroenterology Reports·Morten H Vatn
May 8, 2019·The Journal of Obstetrics and Gynaecology Research·Roberto BrunelliPiero Vernia
Oct 22, 2009·Clinical Reviews in Allergy & Immunology·Norbert Gleicher
Dec 3, 2010·Journal of Crohn's & Colitis·Gert Van AsscheUNKNOWN European Crohn's and Colitis Organisation (ECCO)
Dec 3, 2010·Journal of Crohn's & Colitis·R E MountifieldJ M Andrews
Jan 5, 2016·Digestive Diseases and Sciences·Sarah SheibaniUma Mahadevan
May 4, 2012·British Journal of Haematology·Bethan Myers
Mar 29, 2019·The American Journal of Gastroenterology·Ariella Bar-Gil ShitritSorina Grisaru-Granovsky
Mar 22, 2013·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Karolina PazianaVincent Armenti
Aug 13, 2013·Archives of Gynecology and Obstetrics·Bram P Wispelwey, Eyal Sheiner
Jan 17, 2014·Gut·C Janneke van der WoudeSilvio Danese
Jul 16, 2019·Journal of Clinical Gastroenterology·Parul TandonVivian W Huang
Sep 10, 2014·Alimentary Pharmacology & Therapeutics·H SchulzeA Dignass
Jun 19, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S KilleenJ Hartley

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
J R HutsonGideon Koren
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
M C BushJ L Stone
The Annals of Pharmacotherapy
Myla E MorettiGideon Koren
© 2022 Meta ULC. All rights reserved