PMID: 2104579Jan 1, 1990Paper

Relapsing post-hepatitis aplastic anemia. Immunosuppressive therapy

Clinical Pediatrics
K ShannonM A Koerper

Abstract

A 20-month-old Hispanic male developed severe aplastic anemia after an episode of non-A, non-B hepatitis. Prompt and complete recovery of all hematopoietic cell lines occurred after treatment with antithymocyte globulin (ATG) and high-dose corticosteroids. Severe aplasia recurred two months later coincident with a mild upper respiratory infection. A second course of immunosuppressive therapy was followed by complete, sustained improvement. The authors' experience provides clinical evidence indicating that immunologic mechanisms are important in the treatment of severe post-hepatitis aplastic anemia. Children in whom aplastic anemia recurs after immunosuppressive treatment may respond to a second course of therapy.

References

May 1, 1986·The American Journal of the Medical Sciences·W C WangG J Presbury
Jan 31, 1985·The New England Journal of Medicine·N C ZoumbosN S Young
Feb 1, 1982·The Journal of Pediatrics·M S Cairo, R L Baehner
Jan 1, 1983·The American Journal of Medicine·J B ZeldisR P Gale
Jan 20, 1983·The New England Journal of Medicine·R ChamplinR P Gale
Sep 1, 1984·Scandinavian Journal of Haematology·S OzsoyluS Minassazi
May 1, 1984·Annals of Internal Medicine·K A FoonR P Gale

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Citations

Apr 10, 1997·The New England Journal of Medicine·K E BrownN S Young
Sep 3, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L BathlaA N Langnas

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