Relation between axon morphology in C1 spinal cord and spatial properties of medial vestibulospinal tract neurons in the cat

Journal of Neurophysiology
S I PerlmutterB W Peterson

Abstract

Twenty-one secondary medial vestibulospinal tract neurons were recorded intraaxonally in the ventromedial funiculi of the C1 spinal cord in decerebrate, paralyzed cats. Antidromic stimulation in C6 and the oculomotor nucleus identified the projection pattern of each neuron. Responses to sinusoidal, whole-body rotations in many planes in three-dimensional space were characterized before injection of horseradish peroxidase or Neurobiotin. The spatial response properties of 19 neurons were described by a maximum activation direction vector (MAD), which defines the axis and direction of rotation that maximally excites the neuron. The other two neurons had spatio-temporal convergent behavior and no MAD was calculated. Collateral morphologies were reconstructed from serial frontal sections to reveal terminal fields in the C1 gray matter. Axons gave off multiple collaterals that terminated ipsilaterally to the stem axon. Collaterals of individual axons rarely overlapped longitudinally but projected to similar regions in the ventral horn when viewed in transverse sections. The number of primary collaterals in C1 was different for vestibulo-collic, vestibulo-oculo-collic, and C6-projecting neurons: on average one every 1.34, 1.72, and 4...Continue Reading

References

Jan 1, 1979·Progress in Brain Research·K FukushimaV J Wilson
Nov 1, 1977·The Journal of Physiology·S RapoportV J Wilson
Oct 1, 1978·The Journal of Comparative Neurology·F J RichmondV C Abrahams
Jan 1, 1977·Journal of Neurophysiology·V J WilsonY Uchino
Feb 8, 1992·The Journal of Comparative Neurology·Y ShinodaT Futami
Feb 15, 1991·The Journal of Comparative Neurology·D C Gordon, F J Richmond
Oct 1, 1986·Journal of Neurophysiology·R H SchorV J Wilson
Mar 1, 1986·Journal of Neurophysiology·Y ShinodaT Futami
Mar 1, 1974·Journal of Neurophysiology·V J Wilson, M Maeda
Mar 1, 1984·The Journal of Comparative Neurology·V C Abrahams, J Keane
Jun 10, 1984·The Journal of Comparative Neurology·S J Vanner, P K Rose
Jan 1, 1993·Experimental Brain Research·P S BoltonV J Wilson

❮ Previous
Next ❯

Citations

Nov 17, 2001·Annals of the New York Academy of Sciences·R Boyle
Aug 2, 2013·Journal of Neurophysiology·Patrick A ForbesJean-Sébastien Blouin
Nov 17, 2001·Annals of the New York Academy of Sciences·B W PetersonG C Peng
Mar 18, 2003·The Journal of Comparative Neurology·Ethan Gahtan, Donald M O'Malley
Mar 29, 2011·Experimental Brain Research·Jay M Goldberg, Kathleen E Cullen
Jan 27, 2015·Frontiers in Integrative Neuroscience·Patrick A ForbesJean-Sébastien Blouin
Jul 22, 2018·Frontiers in Neurology·Patrick A ForbesJean-Sébastien Blouin
Apr 16, 2003·Methods : a Companion to Methods in Enzymology·Donald M O'MalleyEthan Gahtan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.