Relation between B-mode gray-scale median and clinical features of carotid stenosis vulnerability

Annals of Vascular Surgery
Joé L KolkertClark J Zeebregts

Abstract

Vulnerability of the carotid plaque might be useful as a predictor for ischemic stroke risk. The gray-scale median (GSM) of the carotid plaque at B-mode imaging has been described as an objective tool to quantify vulnerability. However, its use is disputed in the published literature. This study sought to validate the GSM as a predictor for carotid plaque vulnerability. We included 89 consecutive patients (64 men; mean ± SD age: 68 ± 1 years) who were evaluated for carotid endarterectomy. The GSM was derived from preoperative B-mode images and related to the presence of clinical symptoms, the presence of ipsilateral infarction on neuroimaging, and to the number of intraoperative ipsilateral microemboli (ME) detected by transcranial Doppler ultrasonography. In addition, we combined the GSM with its standard deviation (GSM-SD), which we hypothesized to be a measure for plaque heterogeneity and thereby vulnerability. B-mode imaging revealed a wide variety in GSM among all plaques (median: 36; range: 6-89). The GSM could not be related to cardiovascular risk factors and was not different between symptomatic and asymptomatic patients (37.8 ± 8.9 vs 37.6 ± 17.1; P = 0.97). The GSM of plaques in patients with ipsilateral ischemic lesi...Continue Reading

References

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Citations

Dec 10, 2014·Cardiovascular Ultrasound·Kumar V RamnarineThompson G Robinson
Nov 13, 2019·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Stephen J MurphyDominick Jh McCabe
Jul 22, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Catherine N SteffelCarol C Mitchell
Feb 6, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Manwei HuangChun Yuan

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