Relation between blue-on-yellow perimetry and optical coherence tomography in normal tension glaucoma

Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Y ZhongLieqin Xie

Abstract

To assess the relation between blue-on-yellow perimetry (B/YP) indices and optical coherence tomography (OCT) parameters in normal tension glaucoma (NTG) patients and to investigate the diagnostic ability of B/YP and OCT in discriminating NTG from normal eyes. Cross-sectional study. Eighty normal subjects (80 eyes) and 80 NTG patients (80 eyes) were enrolled in the study. All patients underwent white-on-white perimetry, B/YP, and OCT measurement. The correlation between B/YP indices and OCT parameters was analyzed. The area of the receiver operating characteristic (ROC) curve was calculated to discriminate NTG patients from normal subjects. A highly significant correlation was found between B/YP mean deviation (MD) and average thickness of the retinal nerve fibre layer (r2 = 0.707, p = 0.000), and a moderately significant correlation was found between B/YP MD and temporal average (r2 = 0.437, p = 0.010) in the early NTG patients. A mildly or moderately significant correlation was found between B/YP MD and average thickness, inferior average, temporal average, superior maximum, and maximum-minimum (r2 = 0.212-0.498, p = 0.001-0.048) in the moderate or late NTG patients. The area under the ROC curve at the B/YP MD was 0.896, and ...Continue Reading

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Citations

Apr 29, 2015·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Bruno M R FidalgoJohn G Lawrenson

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