PMID: 7459166Jan 1, 1981Paper

Relation between QT interval and heart rate. New design of physiologically adaptive cardiac pacemaker

British Heart Journal
A F Rickards, J Norman

Abstract

The relation between QT interval and heart rate has been studied in a group of patients undergoing physiological exercise, in a group undergoing atrial pacing without exercise, and in a group with complete heart block undergoing exercise at a fixed ventricular rate controlled by cardiac pacing. The expected shortening in QT interval during physiological exercise is only in part the result of the intrinsic effect of increased rate, since patients undergoing atrial pacing to comparable rates show only a small decrease in measured QT interval and patients exercising at fixed rates in heart block exhibit a decreasing QT interval related to the independent atrial rate. QT interval changes appear mainly to be governed by factors extrinsic to heart rate. The physiological control of QT interval has been used to construct a cardiac pacemaker which senses the interval between the delivered stimulus and the evoked T wave, and uses the stimulus-evoked T wave interval to set the subsequent pacemaker escape interval. Thus physiological control of cardiac pacing rate, independent of atrial activity, using conventional unipolar lead systems is possible.

References

Aug 1, 1972·The Journal of Physiology·M Morad, E L Rolett
Jan 1, 1980·British Heart Journal·J R MilneR A Spurrell

❮ Previous
Next ❯

Citations

Aug 1, 1992·Clinical Cardiology·C F Shakespeare, A J Camm
Mar 1, 1993·Clinical Cardiology·D KatritsisA J Camm
Sep 24, 1999·Clinical Cardiology·P Davey, J Bateman
Apr 1, 1983·Pediatric Cardiology·H B Burchell
Oct 27, 2004·Medical & Biological Engineering & Computing·M HexamerJ Werner
Sep 1, 1987·Medical & Biological Engineering & Computing·M MalíkA J Camm
Jul 1, 1987·International Journal of Bio-medical Computing·M MalikA J Camm
Jan 1, 1997·The American Journal of Cardiology·F J JaegerF M Fouad-Tarazi
Nov 15, 1996·Journal of the American College of Cardiology·P KligfieldP M Okin
Feb 11, 1999·Journal of the American College of Cardiology·N M DebbasA J Camm
Apr 2, 2010·Journal of Biopharmaceutical Statistics·Jie Chen, Xin Zhao
Aug 21, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Eugeniusz PilatWlodzimierz Kargul
Dec 1, 1990·Pacing and Clinical Electrophysiology : PACE·M A LandmanN M van Hemel
Feb 26, 1983·British Medical Journal·R M DonaldsonA F Rickards
Mar 10, 1984·British Medical Journal·A F Rickards
Sep 1, 1991·British Heart Journal·N J LinkerD E Ward
Oct 1, 1992·British Heart Journal·M W BaigE J Perrins
May 1, 1985·Postgraduate Medical Journal·R A Kenny, R Sutton
Sep 1, 1993·Pacing and Clinical Electrophysiology : PACE·D T Connelly
Sep 1, 1990·Pacing and Clinical Electrophysiology : PACE·G C KayeA F Mackintosh
Feb 10, 2000·Pacing and Clinical Electrophysiology : PACE·K S NgB L Chia
Nov 1, 1996·Pacing and Clinical Electrophysiology : PACE·F Di GregorioM G Bongiorni
Aug 1, 1997·Pacing and Clinical Electrophysiology : PACE·L P SoucieA S Tang
Mar 1, 1990·Pacing and Clinical Electrophysiology : PACE·J BrouwerK I Lie
Apr 1, 1990·Pacing and Clinical Electrophysiology : PACE·R Sutton
May 1, 1990·Pacing and Clinical Electrophysiology : PACE·L JordaensD L Clement
Apr 1, 1991·Pacing and Clinical Electrophysiology : PACE·A B CurtisK Miller
Jun 1, 1991·Pacing and Clinical Electrophysiology : PACE·A G Hedman
May 1, 1991·Pacing and Clinical Electrophysiology : PACE·H H DickhuthT Meinertz
Nov 24, 1998·Pacing and Clinical Electrophysiology : PACE·J L AnderssonH Schüller
Aug 1, 1992·Pacing and Clinical Electrophysiology : PACE·C P Lau

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.