PMID: 9434670Jan 22, 1998Paper

Relation of colonic transit to functional bowel disease in older people: a population-based study

Journal of the American Geriatrics Society
J M EvansL J Melton

Abstract

The pathophysiology underlying chronic constipation in older people is poorly understood. Our objective was to determine if functional bowel disease (particularly constipation) in this population is associated with risk factors (age, immobility, low dietary fiber intake, and medication use) or directly with slow colonic transit. A previously validated questionnaire was administered to a random sample of older residents (age range 65-104 years, n = 1609) of Olmsted County, MN. A random subset who met standard diagnostic criteria for functional constipation (n = 52) or irritable bowel syndrome (IBS) (n = 55) and a group without gastrointestinal symptoms (n = 93) were selected for further study. Each subject underwent structured interview and physical examination. Total caloric and fiber intake were assessed by dietitian interview, a food frequency questionnaire, and a food diary. Physical activity was assessed using a previously validated instrument. Medication use was determined by self-report, physician interview, and review of medical records. Total and segmental colonic transit was assessed radiographically using radioopaque markers. Total colonic transit times were prolonged in subjects with functional constipation (median 5...Continue Reading

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May 24, 2011·Gastroenterology Clinics of North America·Tobias Zuchelli, Scott E Myers
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