Relation of contractile reserve during low-dose dobutamine echocardiography and angiographic extent and severity of coronary artery disease in the presence of left ventricular dysfunction

The American Journal of Cardiology
Michael L MainI Afridi

Abstract

Contractile reserve, during low-dose dobutamine echocardiography, is frequently used for the assessment of myocardial viability in patients with coronary artery disease (CAD) and left ventricular (LV) dysfunction. Whether contractile reserve is affected by the severity of the underlying CAD is presently unknown. Accordingly, we studied 58 patients with stable CAD and LV dysfunction who underwent coronary angiography and low-dose dobutamine echocardiography. In each vascular region the worst stenosis was identified and quantitated as percent diameter stenosis. Segmental wall motion during echocardiography was scored visually and rest and dobutamine wall motion score indexes were calculated. Contractile reserve was defined as > or = 1 grade improvement in wall motion score of > or = 2 contiguous segments along with > or = 20% reduction in global wall motion score index with dobutamine. There was no difference between patients with (n = 26) and without (n = 32) contractile reserve in percent coronary stenosis (89 +/- 17% vs 87 +/- 17%, p = 0.6), number of coronary arteries with > 50% diameter stenosis (2.0 +/- 0.8 vs 2.2 +/- 0.7, p = 0.4), number of occluded coronary arteries (1.2 +/- 0.9 vs 1.1 +/- 0.9, p = 0.6), or the prevalenc...Continue Reading

References

Aug 1, 1983·Annals of Internal Medicine·M J YoungB L Strom
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Citations

Nov 18, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Calvin ThompsonJoel L Parlow
Dec 4, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Farooq A ChaudhryJonathan S Steinberg
Feb 5, 2010·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Zainab Abdel-Salam, Wail Nammas
Jul 21, 2004·The American Journal of Cardiology·Sharon L Mulvagh

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