Relation of fragmented QRS to tissue Doppler-derived parametersin patients with familial Mediterranean fever

Wiener klinische Wochenschrift
Muhammet Murat CelikAdnan Burak Akcay

Abstract

Familial Mediterranean fever (FMF) may pose a risk for cardiovascular diseases due to continuous inflammatory status observed during the course of the disease. Recently, the presence of fragmented QRS (fQRS) has been recognized as a predictor of myocardial fibrosis. In this study, we aim to investigate the frequency of fQRS and its relation to Doppler-based indices. This study consisted of 80 FMF patients and 30 healthy control subjects. fQRS pattern was defined as the presence of additional R waves or RSR', evidenced by notched R or S wave on electrocardiography (ECG). The patient and the control groups underwent conventional echocardiography and tissue Doppler echocardiography. There was no significant difference between groups regarding age (29 ± 12 vs 29 ± 15). FMF patients exhibited a statistically higher frequency of fQRS (% 56 vs % 13) (p < 0.01). E/Em ratio showed a statistically significant increase in the FMF group with fQRS (p < 0.0001), while the mean Em value was markedly lower (p < 0.0001). FMF patients displayed a statistically significant increase in frequency of fQRS. Doppler-derived diastolic index was statistically significantly impaired in FMF patients with fQRS as compared with the patients without fQRS. In...Continue Reading

References

Oct 23, 1997·Arthritis and Rheumatism·A LivnehM Pras
Mar 21, 1998·Lancet·E Ben-Chetrit, M Levy
Dec 29, 2000·Current Opinion in Cardiology·J Gorcsan
Apr 17, 2001·Hypertension·F SelzerS Manzi
Jan 10, 2002·Annals of the Rheumatic Diseases·C KorkmazH Yazici
Jun 27, 2002·Journal of the American College of Cardiology·Giuseppe SchillaciElmo Mannarino
Sep 10, 2004·The New England Journal of Medicine·Gerard P Aurigemma, William H Gaasch
Feb 1, 2005·Joint, Bone, Spine : Revue Du Rhumatisme·Seyfettin KöklüSedat Kiraz
Jan 16, 2007·Joint, Bone, Spine : Revue Du Rhumatisme·Omer BaşarMeral Calgüneri
Aug 4, 2007·Atherosclerosis·Mustafa CaliskanHaldun Muderrisoglu
Nov 3, 2007·Progress in Cardiovascular Diseases·Mark A MichaelMithilesh K Das
Apr 1, 2008·Joint, Bone, Spine : Revue Du Rhumatisme·Yusuf TavilAtiye Cengel
Jan 22, 2009·JAMA : the Journal of the American Medical Association·Jasmine GrewalPatricia A Pellikka
Mar 11, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Mithilesh K Das, Douglas P Zipes
Oct 7, 2009·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Mohamed HomsiMithilesh K Das
Nov 3, 2009·Current Opinion in Cardiology·Mithilesh K Das, Hicham El Masry
Apr 13, 2010·The Tohoku Journal of Experimental Medicine·Murat YuceFethi Yavuz
Aug 25, 2011·JAMA : the Journal of the American Medical Association·Garvan C KaneRichard J Rodeheffer
Oct 10, 2012·Clinical and Investigative Medicine. Médecine Clinique Et Experimentale·Eyup BuyukkayaAdnan Burak Akcay

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Citations

Nov 3, 2017·Rheumatology International·Rainer HintenbergerHerwig Pieringer

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