Relation of left atrial blood stasis to clinical risk factors in atrial fibrillation

International Journal of Cardiology
Kazumasa OharaHiroshi Inoue

Abstract

The present study was conducted to investigate whether an accumulation of clinical risk factors for thromboembolism would correlate with severity of blood stasis in the left atrium (LA) and aortic atherosclerosis in patients with nonvalvular atrial fibrillation (NVAF). Risk levels of thromboembolism were assessed in 515 (mean age 67.5 years) NVAF patients using CHADS(2) score (an acronym for Congestive heart failure, Hypertension, Age >or=75, Diabetes mellitus, and prior Stroke or transient ischemic attack) to estimate the thromboembolic risk. Spontaneous echocardiographic contrast in the LA (LASEC), left atrial appendage (LAA) peak flow velocity, and severity of atherosclerosis in the descending aorta were determined with transesophageal echocardiography. LASEC was significantly increased, and LAA flow velocity significantly decreased in correlation with an increase in the risk levels, as evaluated by CHADS(2) score (p<0.001). Severity of aortic atherosclerosis also increased in correlation with an increase in the risk levels (p<0.001). Even at the comparable risk level, patients with chronic atrial fibrillation (AF) (n=268) had higher LASEC (p<0.001) and lower LAA flow velocity (p<0.001) than those with paroxysmal AF (n= 52) ...Continue Reading

References

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Citations

Jul 9, 2011·Cardiology Research and Practice·Nadine Hiari
Oct 27, 2015·Expert Review of Cardiovascular Therapy·Herbert B TanowitzAntonio Luiz P Ribeiro
Apr 7, 2009·International Journal of Cardiology·Oben BaysanBaris Bugan
Jul 29, 2010·Journal of Cardiovascular Electrophysiology·Roy BeinartMoussa Mansour
Dec 10, 2009·Korean Circulation Journal·Boris Leithäuser, Jai-Wun Park
Sep 10, 2014·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Hiroshi Inoue
Nov 26, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Hyungjoon ChoSung Ho Hwang

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