Relation of lipid and lipoprotein(a) to ischaemic stroke

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Handan MisirliNuri Yaşar Erenoğlu

Abstract

The relationship of lipids and Lp(a) to ischemic stroke hasn't been established yet. Our aim was to determine lipid profile and vascular risk factors in stroke patients and compare them with control subjects. Seventy-nine consecutive patients with ischemic stroke were analyzed by total cholesterol, HDL-C, LDL-C, triglyceride, Lp(a) and doppler ultrasonography and vascular risk factors were recorded. Thirty control subjects of same ages were compared with the patient group. Lp(a) and lipids were correlated with stroke subtype and carotid atherosclerosis. There was no statistical significance between patients and control subjects related to total cholesterol, triglyceride, HDL-C, LDL-C and Lp(a) (P>0.05). Atherotrombotic and lacunar strokes didn't show any difference correlated with lipids and Lp(a). Hypertension and diabetes mellitus were important risk factors with (OR=4.50, 95% CI=1.25-16.22) and (OR=4.43, 95% CI=1.79-10.93) respectively. These results were statistically significant (P<0.05). Total cholesterol (308.67+/-85.82) and Lp(a) (32.10+/-17.30) values showed statistical significance (P<0.05) in patients with marked stenosis when compared with patients of normal doppler ultrasonography. Hypertension and diabetes mellitu...Continue Reading

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Citations

Jun 24, 2004·Dementia and Geriatric Cognitive Disorders·Enzo EmanueleDiego Geroldi
Jul 29, 2010·Cerebrovascular Diseases·Bernadette Boden-AlbalaLars Berglund
Nov 28, 2014·The International Journal of Neuroscience·Ilona KopytaBeata Sarecka-Hujar
May 5, 2007·Stroke; a Journal of Cerebral Circulation·Barbara SmoldersVincent Thijs
Jun 7, 2006·The American Journal of Bioethics : AJOB·Adil E Shamoo, David B Resnik

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