Relation of mitral valve prolapse to basal left ventricular hypertrophy as determined by cardiac magnetic resonance imaging

The American Journal of Cardiology
Mohammad Imran ZiaSteven Wolff

Abstract

We aimed to characterize the extent and distribution of focal basal left ventricular (LV) hypertrophy in patients with mitral valve prolapse (MVP). Sixty-three patients (mean age: 58 ± 14 years) with MVP and 20 age-matched normal volunteers (mean age: 53 ± 11 years) were assessed using cardiac magnetic resonance imaging. We compared the ratio of basal to mid end-diastolic wall thickness in both groups and correlated it with clinical and imaging parameters. Of the 63 patients, 44 (70%) had posterior leaflet prolapse, 2 (3%) had anterior leaflet prolapse, and 17 (27%) had bileaflet prolapse. There was a significantly increased ratio of basal to mid-ventricular end-diastolic wall thickness in all segments of the left ventricle in those with MVP compared to the controls. The inferolateral (2.1 vs 1.0, p <0.01) and anterolateral (2.1 vs 1.1) ratios (p <0.01) were the greatest compared to the other myocardial segments. The degree of mitral annular excursion had a strong positive correlation with the degree of hypertrophy (r(2) = 0.81, p <0.01) and was an independent predictor in adjusted multivariate analysis (p <0.0001). Age, body mass index, LV end-diastolic volume index, LV end -systolic volume index, LV stroke volume index, degre...Continue Reading

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Citations

Apr 10, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sherryn RambiharZion Sasson
Aug 16, 2016·Circulation. Cardiovascular Imaging·Martina Perazzolo MarraSabino Iliceto
Jun 10, 2020·Scientific Reports·Alessandra ScatteiaSanto Dellegrottaglie
Aug 18, 2018·Journal of the American College of Cardiology·Danai KitkungvanDipan J Shah
Mar 20, 2021·Virchows Archiv : an International Journal of Pathology·Cristina BassoUNKNOWN Association for European Cardiovascular Pathology
Jun 12, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Thushara MadathilPatrick Perier
Oct 12, 2021·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Angélica Romero DazaJavier Sanz

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