Relation of plasma adiponectin levels and aortic stiffness after acute ST-segment elevation myocardial infarction

European Heart Journal. Acute Cardiovascular Care
Sebastian Johannes ReinstadlerBernhard Metzler

Abstract

Pulse wave velocity is a measure of aortic stiffness and an independent predictor of cardiovascular morbidity and mortality. Adiponectin is involved in atherosclerosis and inflammation. In the present study we aimed to explore the association between plasma adiponectin concentrations and pulse wave velocity in the acute phase after ST-segment elevation myocardial infarction (STEMI). Forty-six consecutive STEMI patients (mean age 57 ± 11 years) treated with primary percutaneous coronary intervention (PCI) were enrolled in this cross-sectional study. Plasma adiponectin was measured 2 days after index event by enzyme-linked immunosorbent assay. Aortic pulse wave velocity (PWV) was calculated by the transit-time method with the use of a velocity-encoded, phase-contrast cardiac magnetic resonance protocol. Median plasma adiponectin concentration was 2385 ng/ml (interquartile range 1735-5403). Males had lower plasma adiponectin values than females and current smokers had lower values than non-smokers (all p<0.02). Adiponectin was significantly associated with PWV (r=0.505, p<0.001), age (r=0.437, p=0.002), and total cholesterol (r=0.468, p=0.001). Multiple linear regression analysis revealed adiponectin as a predictor of PWV independ...Continue Reading

References

Mar 7, 2001·American Heart Journal·B A VakiliR B Devereux
Mar 14, 2003·The American Journal of Cardiology·Hasan JilaihawiUNKNOWN Healing and Early Afterload Reducing Therapy Trial Investigators
Apr 15, 2004·JAMA : the Journal of the American Medical Association·Tobias PischonEric B Rimm
Dec 21, 2005·American Journal of Hypertension·Azra Mahmud, John Feely
Aug 17, 2006·The Journal of Clinical Endocrinology and Metabolism·Stefan PilzWinfried März
Sep 27, 2006·European Heart Journal·Stephane LaurentUNKNOWN European Network for Non-invasive Investigation of Large Arteries
Nov 4, 2006·Journal of Hypertension·Nicole M van PopeleJacqueline C M Witteman
Nov 23, 2006·The Journal of Clinical Endocrinology and Metabolism·Jan FrystykBjörn Zethelius
Dec 5, 2006·Metabolism: Clinical and Experimental·Naotake HashimotoShouji Yoshida
Jan 18, 2007·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·W Rathmann, C Herder
Apr 9, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Volker HeroldPeter M Jakob
Aug 28, 2009·Journal of Magnetic Resonance Imaging : JMRI·Heynric B GrotenhuisAlbert de Roos
May 13, 2010·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·El-Sayed H IbrahimRichard D White
Apr 2, 2011·Journal of the American College of Cardiology·João L CavalcanteMouaz H Al-Mallah
Apr 5, 2011·British Journal of Pharmacology·Xiaoyan HuiAimin Xu
Oct 12, 2011·Journal of Atherosclerosis and Thrombosis·Jong Suk ParkHyun Chul Lee
Jan 22, 2013·Atherosclerosis·George NtaiosGeorge N Dalekos

❮ Previous
Next ❯

Citations

Jun 10, 2015·European Heart Journal Cardiovascular Imaging·Sebastian J ReinstadlerBernhard Metzler
Sep 24, 2015·International Journal of Cardiology·Sebastian Johannes ReinstadlerBernhard Metzler
May 12, 2015·Disease Markers·Sebastian Johannes ReinstadlerJohannes Mair
May 12, 2015·Disease Markers·Sebastian Johannes ReinstadlerBernhard Metzler
Jun 24, 2014·International Journal of Cardiology·Sebastian Johannes ReinstadlerBernhard Metzler
Aug 16, 2016·Clinical and Experimental Nephrology·Chang Seong KimUNKNOWN Representing KNOW-CKD Study Group
Jul 16, 2016·British Medical Bulletin·Hans-Josef FeistritzerBernhard Metzler
Feb 15, 2015·European Heart Journal. Acute Cardiovascular Care·Ignacio M SeropianAntonio Abbate
Oct 11, 2015·European Heart Journal. Acute Cardiovascular Care·Hans-Josef FeistritzerBernhard Metzler
Jul 22, 2016·European Heart Journal. Acute Cardiovascular Care·Martin ReindlBernhard Metzler
Feb 1, 2020·Journal of the American Heart Association·Martin ReindlSebastian J Reinstadler
Jan 8, 2017·Clinical Chemistry·Vlad C Vasile, Allan S Jaffe
Jan 8, 2017·Clinical Chemistry·Fred S AppleDavid Morrow
Apr 12, 2018·European Heart Journal. Acute Cardiovascular Care·Martin ReindlBernhard Metzler
Jul 3, 2021·Medicina·Ioana ParaMihai D Porojan
Sep 4, 2021·The International Journal of Cardiovascular Imaging·Ivan LechnerSebastian Johannes Reinstadler

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Software Mentioned

SPSS Statistics

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.