PMID: 9420488Jan 8, 1998Paper

Relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection: cross sectional study

BMJ : British Medical Journal
Hermann BrennerG Adler

Abstract

To assess the relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection. Cross sectional study of patients attending a general practitioner. Active H pylori infection was measured by the 15C-urea breath test and detailed quantitative information on smoking and on alcohol and coffee consumption was obtained by a standardised self administered questionnaire. One general practice in Germany. 447 patients aged 15-79 who had not had peptic ulcer disease or treatment for H pylori infection. Prevalence of H pylori infection according to smoking and alcohol and coffee consumption. Overall prevalence of infection was 21% (94/447). There was no significant relation between smoking and active H pylori infection. Alcohol consumption showed a negative dose-response relation and coffee consumption a positive dose-response relation with active infection. After adjustment for potential confounders, the odds ratios for patients who drank < or = 75 g and > 75 g of ethanol a week compared with non-drinkers were 0.90 (95% confidence interval 0.55 to 1.59) and 0.33 (0.16 to 0.68), respectively (P value for trend 0.005, assuming that 1 litre of beer and 0.51 of wine contain on average 50 g of ethanol in south Ger...Continue Reading

Citations

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