Relation of the segregative origin of chromosome replication to the origin of replication after amino acid starvation.

Journal of Bacteriology
H Eberle, K G Lark

Abstract

Cultures of Escherichia coli 15T(-) and K-12 were labeled with (3)H-thymine before, during, and after amino acid starvation. The number of labeled segregating units was measured by autoradiography of microcolonies derived from the labeled cells. In both strains, labels inserted before starvation and during starvation appeared to segregate as if incorporated into the same polynucleotide strands. However, labels inserted during and after starvation segregated as if incorporated into different polynucleotide strands. In view of previous data, it was concluded that replication after amino acid starvation originates from the region of the chromosome which serves as the origin for replication during normal growth and division.

References

Nov 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·M Abe, J Tomizawa
Mar 28, 1968·Journal of Molecular Biology·B WolfD A Glaser
May 1, 1968·Journal of Bacteriology·C E Helmstetter
Aug 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·M L Pato, D A Glaser
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·L G Caro, C M Berg
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·B WolfD A Glaser
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·R Bird, K G Lark
Nov 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·K G Lark, R E Bird
Apr 1, 1961·Journal of Molecular Biology·O MAALOE, P C HANAWALT
Aug 1, 1964·Journal of Molecular Biology·R H PRITCHARD, K G LARK

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Citations

Jan 1, 1973·Zeitschrift für allgemeine Mikrobiologie·M Hilliger, F Bergter
Apr 5, 1978·Journal of Molecular Biology·K Drlica, M Snyder

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