Relations among circulating monocytes, dendritic cells, and bacterial translocation in patients with intestinal obstruction.

World Journal of Surgery
Hisanori ShiomiTohru Tani


Little evidence is available regarding the relations among circulating monocytes, dendritic cells (DCs), and bacterial translocation (BT) in patients with intestinal obstruction. We investigated alterations in DCs in mesenteric lymph nodes (MLNs), circulating immune cells (white blood cell, lymphocyte, and monocyte counts), and BT to MLNs in 21 patients undergoing abdominal surgery because of intestinal obstruction. We also examined whether BT correlated with the development of perioperative systemic inflammatory response syndrome (SIRS) and postoperative septic complications. BT subsequent to intestinal obstruction was observed in 7 (33%) patients. Preoperative circulating immune cell counts were significantly lower in BT-positive patients than those in BT-negative patients. The presence of preoperative SIRS was also significantly related to BT-positive status. A preoperative monocyte count <290/mm(3) was the best predictive factor for BT in MLNs during intestinal obstruction: sensitivity 85.7%; specificity 92.3%; positive and negative predictive values 85.7% and 92.9%, respectively. The area under the receiver operating characteristic curve was 0.944. The expression of S-100 protein-positive DCs in MLNs significantly increase...Continue Reading


Jan 1, 1992·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·M ShamotoK Nomoto
Apr 1, 1990·American Journal of Surgery·E A DeitchR D Specian
Jun 1, 1995·Diseases of the Colon and Rectum·P M SagarD Johnstone
Dec 1, 1994·The British Journal of Surgery·A F HorganW O Kirwan
Sep 1, 1994·Gastroenterology·P C SedmanD Johnstone
Jan 19, 1994·JAMA : the Journal of the American Medical Association·A L Beal, F B Cerra
Jan 20, 1997·The Journal of Experimental Medicine·C WinzlerP Ricciardi-Castagnoli
Apr 1, 1998·Nature·J Banchereau, R M Steinman
Dec 2, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·K B KirklandD J Sexton
Aug 18, 2004·The Journal of Surgical Research·Mashkoor A ChoudhryMohammed M Sayeed
Jan 15, 2005·World Journal of Surgery·Yoshio TakesueTaijiro Sueda
Mar 19, 2005·Burns : Journal of the International Society for Burn Injuries·Michael J KavanaughMashkoor A Choudhry
Mar 19, 2005·World Journal of Surgery·Satoshi OnoHidetaka Mochizuki
Jun 16, 2005·Seminars in Immunology·Beatriz LeónCarlos Ardavín
Sep 9, 2005·Frontiers in Bioscience : a Journal and Virtual Library·Edwin A DeitchVicki L Kaise
Nov 17, 2005·The British Journal of Surgery·J MacFieC J Mitchell
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