PMID: 8589767Oct 1, 1995Paper

Relations of body fat and fat distribution to the serum lipid, apolipoprotein and insulin concentrations of Samoan men and women

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
D J GalanisP D Levinson

Abstract

To examine relations between obesity and serum concentrations of lipoprotein cholesterol, apolipoproteins, triglycerides and insulin in American and Western Samoans. Associations are also described between these CHD risk factors and abdominal adiposity, and the potential mediating role of insulin in these relationships is examined. Cross-sectional, using a sub-sample from an observational epidemiological study of cardiovascular disease risk factors among Samoans. Obesity is estimated by the body mass index (BMI), and fat distribution by the abdomen-hip circumference ratio (AHR). All biochemical parameters were measured in the fasted stated. The sub-sample is 178 men and 147 women who were free from hypertension, diabetes and heart disease. In multivariate linear regression analyses in men the BMI was positively associated with levels of total cholesterol, the total-HDL cholesterol ratio, apolipoprotein B, and the log of triglyceride and insulin concentrations, and negatively associated with HDL and HDL2 cholesterol. The quadratic term for BMI was also found to be significantly predictive of all metabolic parameters in men, except for the log of serum insulin concentrations. Among the women, in contrast, BMI levels were signific...Continue Reading

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