Relationship between acute fetal distress and maternal-placental-fetal circulations in severe preeclampsia

Acta Obstetricia Et Gynecologica Scandinavica
J M Yang, K G Wang


Hypoxic complications are thought to be the result of vascular lesions in the maternal-placental or fetal-placental circulation, with a resultant decrease in blood flow. This study was designed 1) to explore what kind of pathophysiological changes occur in the maternal-placental-fetal circulations associated with acute fetal distress, and 2) to determine whether umbilical velocimetry can be used as a predictor of acute hypoxia in severe preeclampsia. Eighty-nine cases of severe preeclampsia, who had Doppler ultrasonography, maternal blood chemistry and hematogram examinations all performed within two days of delivery or fetal death, were studied. According to the absence or presence of acute fetal distress as determined by the fetal heart rate pattern, patients were divided into two groups: distress group and non-distress group. There was no significant difference between the two groups in maternal general status. However, patients in the distress group had a significantly shorter gestation age on admission and at delivery (p < 0.00001). In the distress group, the perinatal outcome was poor. Newborns in the distress group had, significantly, a lower birthweight, and a higher incidence of SGA, 1-min Apgar scores of less than 7, ...Continue Reading


Jun 24, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Dimitrios KassanosGeorge Creatsas
Dec 10, 2014·PloS One·Tayyba Y AliRaheela N Khan
Apr 20, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·L Geerts, H J Odendaal
Oct 20, 2018·Cell and Tissue Research·Antonio Pérez-PérezVíctor Sánchez-Margalet
Apr 28, 2019·International Journal of Molecular Sciences·Zahra MasoumiStefan R Hansson

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