Relationship between adiponectin, glycemic control and blood lipids in diabetic type 2 postmenopausal women with and without complication of ischemic heart disease

Clinica Chimica Acta; International Journal of Clinical Chemistry
Farhan JaleelM Ataur Rahman

Abstract

Recently major adipocytokine, adiponectin, are thought to play important roles in the regulation of cardiovascular and metabolic homeostasis. We compared serum adiponectin concentrations and lipid profile in diabetic patients with and without complication of cardiovascular disease in postmenopausal women. We included 120 female subjects between the age of 45 and 60 years. The subjects were divided into 3 groups and each group comprised of 40 subjects. First group comprised of normal healthy controls, second group diabetic type 2 patients with no history of ischemic heart disease (IHD) and the third group diabetic patients with IHD. Serum adiponectin concentrations, serum triglycerides, cholesterol, LDL cholesterol and HDL cholesterol concentrations were determined. Values of fasting and random blood glucose, serum triglycerides, cholesterol, LDL cholesterol were significantly increased (P<0.001) in diabetic patients with IHD as compared with normal control subjects except for serum adiponectin and HDL cholesterol concentrations, which were significantly decreased (P<0.001) in diabetic patients and diabetic patients with IHD group. When values of cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, fasting and random bl...Continue Reading

References

Mar 31, 2000·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Y OkamotoY Matsuzawa
Jun 24, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·C LacquemantJ Ruiz

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Citations

Aug 22, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Katsuko MiyanagaTsutomu Kazumi
Dec 6, 2012·ISRN Oncology·Vajihe IzadiLeila Azadbakht
Feb 23, 2013·International Journal of Endocrinology·Chung-Hua Hsu
Jan 14, 2016·Journal of Diabetes Research·Lei XiaoTianLiang ZiWen
May 18, 2007·Journal of Clinical Laboratory Analysis·Mohammad Taghi GoodarziShahram Haddadinezhad
Mar 26, 2013·Primary Care Diabetes·Megan BrownChristopher Scott Owings

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