Relationship between annual influenza vaccination and winter mortality in diabetic people over 65 years

Human Vaccines & Immunotherapeutics
Teresa Rodriguez-BlancoNeus Saún

Abstract

Influenza is an important cause of morbidity and mortality in older people, especially in those with some high-risk conditions such as diabetes mellitus. This study assessed the relationship between influenza vaccination status and winter mortality among diabetics 65 y and over during four consecutive influenza seasons. Population-based cohort study including 2,650 community-dwelling individuals 65 y or older with diabetes mellitus followed between January 2002 and April 2005 in Tarragona, Spain. Influenza vaccination status was evaluated every year of the study and the primary endpoint was considered all-cause death during the study period. Deaths were classified as occurring within influenza periods (January-April) or non-influenza periods. The relationship between vaccination and winter mortality was evaluated by multivariable discrete-time hazard models. Influenza immunization was associated with a reduction of 33% (95% confidence interval: 4-53) in the adjusted risk of all-cause mortality throughout the overall influenza periods 2002-2005. The attributable risk to vaccination in reducing mortality was 13.5 per 100,000 person-weeks within influenza periods, estimating that one death was prevented for every 435 annual vaccin...Continue Reading

References

Oct 1, 1995·Annals of Internal Medicine·P A GrossR A Levandowski
Jan 24, 1998·Epidemiology and Infection·A J ColquhounN T Raymond
Sep 17, 1998·Archives of Internal Medicine·K L NicholT von Sternberg
Nov 7, 1998·BMJ : British Medical Journal·D G Altman
May 14, 2003·Archives of Internal Medicine·Bettie C G VoordouwBruno H C Stricker
Jun 14, 2003·European Journal of Public Health·Antonio Sarría-Santamera, Julia Timoner
Jul 17, 2003·British Journal of Cancer·T G ClarkD G Altman
Dec 25, 2003·Diabetes Care·Steven A SmithUNKNOWN American Diabetes Association
Nov 4, 2004·JAMA : the Journal of the American Medical Association·A C G VoordouwBruno H Ch Stricker
Feb 16, 2005·Archives of Internal Medicine·Lone SimonsenMark A Miller
Jul 27, 2005·Diabetes Care·Rodrigo Jiménez-GarcíaAngel Gil de Miguel
Nov 14, 2006·Vaccine·Chong-Shan WangPesus Chou
Jun 19, 2007·International Journal of Clinical Practice·A Vila-CórcolesN Saún
Sep 28, 2007·The Lancet Infectious Diseases·Lone SimonsenLisa A Jackson
Oct 5, 2007·The New England Journal of Medicine·Kristin L NicholEelko Hak
Nov 11, 2008·European Heart Journal·Cinta de DiegoUNKNOWN EPIVAC Study Group

❮ Previous
Next ❯

Citations

Apr 17, 2013·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Manuel Gargallo Fernández
Jun 13, 2016·Primary Care Diabetes·Ludovic CasanovaPierre Verger
Nov 7, 2016·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Cornelius RemschmidtThomas Mertens
Feb 14, 2013·Human Vaccines & Immunotherapeutics·Isabel Jimenez-TrujilloRodrigo Jiménez-García

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Influenza and Other Respiratory Viruses
Q Sue HuangBruce Adlam
Diabetes Research and Clinical Practice
Rodrigo Jiménez-GarcíaAngel Gil de Miguel
Diabetes Care
American Diabetes Association
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Jeffrey C KwongLaura C Rosella
© 2022 Meta ULC. All rights reserved